Results 191 to 200 of about 12,137,319 (407)

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

LONG TERM EXPERIENCE WITH BOSENTAN IN PATIENTS WITH PULMONARY ARTERIAL HYPERTENSION (PAH) ASSOCIATED WITH ADVANCED IDIOPATHIC PULMONARY FIBROSIS (IPF) AND INTERSTITIAL LUNG DISEASE (ILD): A RETROSPECTIVE CASE SERIES [PDF]

, 2005
Ganesh Raghu, Jennifer Hayes, C. Spada, Jeffrey Moniz, Steve Yang   +4 more
openalex   +1 more source

Inhaled antibiotics to improve efficacy and safety in the treatment of upper airway and lung inflammatory diseases

, 2021
Drozdov Vn, Konstantin I. Arefev, S. Yu. Serebrova, И. А. Комиссаренко, Е. В. Ших, А. К. Стародубцев, T. V. Marin, S. S. Sharonova   +7 more
openalex   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

P9 Cough Is Prevalent In Higher Proportion Of Older Patients With Both Idiopathic Pulmonary Fibrosis And Non-specific Interstitial Lung Disease [PDF]

, 2014
G. Saini, Tricia M. McKeever, Rebecca Braybrooke, Richard Hubbard, Gísli Jenkins, Robert Marshall, Pauline T. Lukey, John Simpson   +7 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Real-world treatment persistence and predictive factors for discontinuation of antifibrotic therapies in patients with idiopathic pulmonary fibrosis: a post-hoc analysis of two multicenter observational cohort studies in Poland

Frontiers in Pharmacology
BackgroundPersistence with antifibrotic medications in patients with idiopathic pulmonary fibrosis (IPF) is crucial for long-term outcomes. However, real-world data regarding treatment persistence patterns in IPF are scarce.MethodsWe conducted a post hoc
Sebastian Majewski, Katarzyna Górska, Katarzyna B. Lewandowska, Magdalena M. Martusewicz-Boros, Małgorzata Sobiecka, Wojciech J. Piotrowski   +5 more
doaj   +1 more source

496 Mutations of Surfactant-Related Genes Sp-B, Sp-C and Abca3 in Unexplained Aleolar/Interstitial Lung Disease in Newborn and Infants [PDF]

, 2010
Donatella Peca, Renata Boldrini, Stefania Petrini, Renato Cutrera, Olivier Danhaive   +4 more
openalex   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source