Results 191 to 200 of about 1,682,964 (357)

Dust and Lung Disease [PDF]

, 1945

openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Liposome-Based Nanoparticle Delivery Systems for Lung Diseases: Opportunities and Challenges. [PDF]

Int J Nanomedicine
Zhang X, Tu S, Tian J, Liang Y, An Y, Zhang T, Guan H, Xiong B, Qin L, Li Y, Gong L.   +10 more
europepmc   +1 more source

RIGHT VENTRICULAR HYPERTROPHY AND THE SMALL PULMONARY ARTERIES IN CHRONIC LUNG DISEASE [PDF]

, 1963
W. R. L. James, A. J. Thomas
openalex   +1 more source

MALIGNANT DISEASE OF THE LUNG [PDF]

BMJ, 1931
openaire   +4 more sources

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Notes and Observations on Diseases of the Heart and Lungs [PDF]

T. Shapter
openalex   +3 more sources

Heterogeneity of Cellular Senescence, Senotyping, and Targeting by Senolytics and Senomorphics in Lung Diseases. [PDF]

Int J Mol Sci
Ozdemir SA, Faizan MI, Kaur G, Shaikh SB, Ul Islam K, Rahman I.   +5 more
europepmc   +1 more source

COMPARATIVE FREQUENCY OF DISEASE OF THE HEART AND EMPHYSEMA OF THE LUNG IN ST. GEORGE'S HOSPITAL AND THE EDINBURGH ROYAL INFIRMARY [PDF]

Thos. K. Chambers
openalex   +1 more source