Results 111 to 120 of about 12,551,552 (363)

ARTP statement on pulmonary function testing

BMJ Open Respiratory Research, 2020
James H Hull, Brendan G Cooper, Julie K Lloyd   +2 more
doaj   +1 more source

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Smoking in Health Science Students with Asthma

Canadian Respiratory Journal, 2004
It is expected that asthmatic students in a health science department would avoid the hazards of cigarette smoking due to the knowledge they gain through their studies.
Georgios Krommydas, Evangelia Kotrotsiou, Vasilios Raftopoulos, Theodosios Paralikas, Konstantinos I Gourgoulianis, Paschalis-Adam Molyvdas   +5 more
doaj   +1 more source

Exuberant fibroblast activity compromises lung function via ADAMTS4

Nature, 2020
David F. Boyd, E. Allen, A. Randolph, Xi-zhi J. Guo, Yunceng Weng, C. Sanders, Resha Bajracharya, Natalie K. Lee, C. Guy, P. Vogel, Wenda Guan, Yimin Li, Xiaoqing Liu, T. Novak, M. Newhams, Thomas P. Fabrizio, Nicholas Wohlgemuth, Peter M. Mourani, T. Wight, S. Schultz‐Cherry, S. Cormier, Kathryn Shaw-Saliba, A. Pekosz, R. Rothman, Kuan-Fu Chen, Zi-feng Yang, R. Webby, N. Zhong, J. Crawford, P. Thomas, Palisi Pediatric Intensive Care Influenza Investigators   +30 more
semanticscholar   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Lung function in patients with left-to-right shunts. [PDF]

, 1967
H Davies, N Gazetopoulos
openalex   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

MORTALITY IN COALWORKERS' PNEUMOCONIOSIS RELATED TO LUNG FUNCTION: A PROSPECTIVE STUDY [PDF]

, 1965
P. D. Oldham, C. E. Rossiter
openalex   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

A comparison of respiratory oscillometry and spirometry in idiopathic pulmonary fibrosis: performance time, symptom burden and test–retest reliability

ERJ Open Research
Study question In large multinational patient surveys, spirometry (which requires repeated, reproducible maximal efforts) can be associated with cough, breathlessness and tiredness, particularly in those with idiopathic pulmonary fibrosis (IPF ...
Suhani Patel, Karl P. Sylvester, Zhe Wu, Serena Rhamie, Peter Dickel, Toby M. Maher, Philip L. Molyneaux, Peter M.A. Calverley, William D-C. Man   +8 more
doaj   +1 more source