Results 61 to 70 of about 14,390,763 (310)
A Novel Curcumin-Based Drug Powder Inhalation Medicine for Chronic Obstructive Pulmonary Disease
Bioinorganic Chemistry and Applications, 2021 The dry powder inhaler is a new form of drug delivery that is widely used as an alternative to traditional drug delivery methods, addressing the shortcomings of traditional drug delivery methods and obtaining better therapeutic results.
Qin Shen +4 more
doaj +1 more source
Effects of Long-Term Exposure to Traffic-Related Air Pollution on Lung Function in Children
Current Allergy and Asthma Reports, 2017 Lung function in early life has been shown to be an important predictor for peak lung function in adults and later decline. Reduced lung function per se is associated with increased morbidity and mortality.
E. S. Schultz, A. Litonjua, E. Mélen
semanticscholar +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Journal of Rehabilitation Medicine, 2020 Post-polio patients sometimes complain about the occurrence of breathing difficulties decades after the polio infection. We have examined 40 post-polio patients who have had respiratory or non-respiratory poliomyelitis for at least 30 years in an attempt to elucidate whether hypoventilation is common and to what extent certain symptoms and simple lung ...
A, Blomstrand, B, Bake
openaire +2 more sources
Lung function predicts lung cancer [PDF]
European Respiratory Journal, 2010 To the Editors: We read with great interest the recent article by Calabro et al. 1 showing the close relationship between obstructive lung disease and lung cancer. In particular, we are interested in their suggestion that spirometry might play a very useful role in improving patient selection for targeted lung cancer screening.
R. Young, R. Hopkins
openaire +1 more source
Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease.
New England Journal of Medicine, 2015 BACKGROUND Chronic obstructive pulmonary disease (COPD) is thought to result from an accelerated decline in forced expiratory volume in 1 second (FEV1) over time.
P. Lange +18 more
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Functional vascularized lung grafts for lung bioengineering [PDF]
Science Advances, 2017 We propose a new approach to lung regeneration by replacement of damaged epithelium with full preservation of lung vasculature.
N. Valerio Dorrello +12 more
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cell Reports, 2018 Summary: Cardiomyocytes from the apex but not the base of the heart increase their contractility in response to β2-adrenoceptor (β2AR) stimulation, which may underlie the development of Takotsubo cardiomyopathy.
Peter T. Wright +16 more
doaj +1 more source