Results 51 to 60 of about 1,239,389 (314)

GSTCD and INTS12 Regulation and Expression in the Human Lung [PDF]

, 2013
Genome-Wide Association Study (GWAS) meta-analyses have identified a strong association signal for lung function, which maps to a region on 4q24 containing two oppositely transcribed genes: glutathione S-transferase, C-terminal domain containing (GSTCD ...
Swan, Caroline, Erik Melén (276082), Ma'en Obeidat, Hao Ke, S. Miller (3494552), Nelson, CP, I. Sayers (3494558), Henry, Amanda P., Probert, Kelly, C. Swan (7390268), Sayers, Ian, Miller Suzanne, K. Probert (7667498), Hodge, E, Maxime Lamontagne (116448), Ma’en Obeidat (460144), Ushey Kevin, Hao, Ke, Dirkje S Postma, Kevin Ushey (181019), Tobin, MD, Wain, LV, Amanda P. Henry (460148), Dirkje S. Postma (101740), Y. Bossé (7628753), Lamontagne, M, Miller, Suzanne, Obeidat Ma’en, Wain, Louise V., Melén Erik, María Soler Artigas (7603997), Caroline Swan (37264), Ceri E. Stewart (460151), Obeidat, Ma'en, Stewart, CE, E. Melén (3494549), Soler Artigas, María, Bossé, Y, Caroline Swan, Kelly Probert (460146), Nelson, Carl P., Nelson Carl P., Stewart Ceri E., Postma, Dirkje S., Lamontagne Maxime, Probert, K, Ceri E Stewart, Hao, K, Carl P Nelson, Hall Ian P., Erik Melén, Ke Hao, Postma Dirkje S., Artigas, Maria Soler, K. Hao (7628756), Billington Charlotte K., Kevin Ushey, Charlotte K. Billington (460147), D. S. Postma (3809164), M. Obeidat (7628729), María Soler Artigas (110124), Louise V. Wain (7588511), Martin D Tobin, Carl P. Nelson (460150), Ushey, Kevin, Ian Sayers, C. P. Nelson (7591670), Tobin Martin D., Ian P. Hall (110307), Hodge, Emily, Ian P Hall, Maxime Lamontagne, Louise V Wain, C. K. Billington (7667501), Emily Hodge (460149), Ke Hao (50181), Wain Louise V., Bossé Yohan, Sayers, I, Ushey, K, Hall, IP, Louise V. Wain (110260), Amanda P Henry, Emily Hodge, Artigas, MS, C. E. Stewart (7627559), Melen, Erik, E. Hodge (7643807), Billington, Charlotte K., Suzanne Miller, Obeidat, Ma�en, Henry Amanda P., Soler Artigas, Mar�a, Hodge Emily, Probert Kelly, Obeidat, M, Lamontagne, Maxime, Billington, CK, K. Ushey (7667507), Boss�, Yohan, Melén, E, A. P. Henry (7667504), Sayers Ian, Swan, C, Kelly Probert, Stewart, Ceri E., Obeidat, Ma’en, Ian Sayers (37266), Martin D. Tobin (7581161), Artigas María Soler, Henry, AP, Postma, DS, Yohan Bossé (69571), Hall, Ian P., Tobin, Martin D., Suzanne Miller (460145), Yohan Bossé, M. Lamontagne (7667510), Swan Caroline, Martin D. Tobin (110311), Mel�n, Erik, Miller, S, Charlotte K Billington, María Soler Artigas, Bosse, Yohan, I. P. Hall (7628774)   +125 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

International consensus on lung function testing during the COVID-19 pandemic and beyond

ERJ Open Research, 2022
Coronavirus disease 2019 (COVID-19) has negatively affected the delivery of respiratory diagnostic services across the world due to the potential risk of disease transmission during lung function testing.
Aisling McGowan, Pierantonio Laveneziana, Sam Bayat, Nicole Beydon, P.W. Boros, Felip Burgos, Matjaž Fležar, Monika Franczuk, Maria-Alejandra Galarza, Adrian H. Kendrick, Enrico Lombardi, Jellien Makonga-Braaksma, Meredith C. McCormack, Laurent Plantier, Sanja Stanojevic, Irene Steenbruggen, Bruce Thompson, Allan L. Coates, Jack Wanger, Donald W. Cockcroft, Bruce Culver, Karl Sylvester, Frans De Jongh   +22 more
doaj   +1 more source

Breastfeeding and lung function at school age: does maternal asthma modify the effect? [PDF]

, 2012
The evidence for an effect of breastfeeding on lung function is conflicting, in particular whether the effect is modified by maternal ...
Frey, U, Spycher, B D, Frey, Urs, Strippoli, Marie-Pierre F., Beardsmore, Caroline S, Dogaru, Cristian, Spycher, Ben D, Kuehni, Claudia E, Kuehni, Claudia E., Dogaru, Cristian M., Silverman, Michael, Strippoli, M P, Silverman, M   +12 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Parental smoking and lung function in children: an international study.

, 2006
RATIONALE: Both prenatal and postnatal passive smoking have been linked with respiratory symptoms and asthma in childhood. Their differential contributions to lung function growth in the general children's population are less clear.
Hruba, F., Antova, Temenuga, Moshammer, Hanns, Luttmann-Gibson, H., Slachtova, H., Pattenden, Sam, Zlotkowska, Renata, Neuberger, M.A., Fletcher, T., Antova, T., Gehring, Ulrike, Hruba, Frantiska, Hoek, G., Neuberger, Manfred A, Pattenden, S., Fletcher, Tony, Rudnai, P., Rudnai, Peter, Slachtova, Hana, Moshammer, H., Gehring, U., Hoek, Gerard, Zlotkowska, R., Luttmann-Gibson, Heike   +23 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Lung clearance index in detection of post-transplant bronchiolitis obliterans syndrome

ERJ Open Research, 2019
Background Long-term outcomes after lung transplantation are often limited by the development of obliterative bronchiolitis (OB), which is clinically defined using spirometry as bronchiolitis obliterans syndrome (BOS). Lung clearance index (LCI), derived
Madeleine Driskel, Alex Horsley, Laurice Fretwell, Nigel Clayton, Mohamed Al-Aloul   +4 more
doaj   +1 more source