Results 31 to 40 of about 1,914,004 (302)

Concurrent micro- to macro-cardiac electrophysiology in myocyte cultures and human heart slices

Scientific Reports, 2018
The contact cardiac electrogram is derived from the extracellular manifestation of cellular action potentials and cell-to-cell communication. It is used to guide catheter based clinical procedures.
Rasheda A. Chowdhury, Konstantinos N. Tzortzis, Emmanuel Dupont, Shaun Selvadurai, Filippo Perbellini, Chris D. Cantwell, Fu Siong Ng, Andre R. Simon, Cesare M. Terracciano, Nicholas S. Peters   +9 more
doaj   +1 more source

Severe acute respiratory failure due to a multifactorial diffuse alveolar haemorrhage

Respirology Case Reports, 2020
Diffuse alveolar haemorrhage (DAH) is a life‐threatening syndrome caused by infection, coagulation disorders or autoimmune diseases. We here report the case of an 81‐year‐old male subject affected by a multifactorial DAH, in which the bleeding was ...
Ernesto Crisafulli, Barbara Burgazzi, Maria Majori, Walter Serra, Alfredo Chetta   +4 more
doaj   +1 more source

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

Frontiers in Physiology, 2018
Introduction: We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains.
Peter T. Wright, Jose L. Sanchez-Alonso, Carla Lucarelli, Carla Lucarelli, Anita Alvarez-Laviada, Claire E. Poulet, Sean O. Bello, Giuseppe Faggian, Cesare M. Terracciano, Julia Gorelik   +9 more
doaj   +1 more source

HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium [PDF]

, 2013
Background: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation.
Bonney, Megan, Borchers, Christoph H., Brodsky, Kelley, Eckle, Tobias, Eltzschig, Holger K., Han, Jun, Kominsky, Douglas J., Mariani, Thomas J., Mittelbronn, Michel Guy André, Packard, Thomas   +9 more
core   +3 more sources

Ultrasound evaluation of diaphragmatic function in patients with idiopathic pulmonary fibrosis: a retrospective observational study

Respiratory Research, 2023
Introduction The diaphragm function assessed by ultrasound has been well-studied in COPD, asthma, and intensive care. However, there are only a few studies on diffuse interstitial lung disease, while dyspnea and quality of life are major issues in the ...
Jules Milesi, Alain Boussuges, Paul Habert, Julien Bermudez, Martine Reynaud-Gaubert, Stéphane Delliaux, Fabienne Bregeon, Benjamin Coiffard   +7 more
doaj   +1 more source

Lung Development Genes and Adult Lung Function

American Journal of Respiratory and Critical Care Medicine, 2020
Rationale: Poor lung health in adult life may occur partly through suboptimal growth and development, as suggested by epidemiological evidence pointing to early life risk factors.Objectives: To systematically investigate the effects of lung development genes on adult lung function.Methods: Using UK Biobank data, we tested the association of 391 genes ...
Laura Portas, Miguel Pereira, Seif O. Shaheen, Annah B. Wyss, Stephanie J. London, Peter G. J. Burney, Matthew Hind, Charlotte H. Dean, Cosetta Minelli   +8 more
openaire   +4 more sources

Absolute electrical impedance tomography (aEIT) guided ventilation therapy in critical care patients: simulations and future trends [PDF]

, 2010
Thoracic electrical impedance tomography (EIT) is a noninvasive, radiation-free monitoring technique whose aim is to reconstruct a cross-sectional image of the internal spatial distribution of conductivity from electrical measurements made by injecting ...
Brown, B.H., Denai, M., Mahfouf, M., Mills, G.H., Mohamad-Samuri, S., Panoutsos, G.   +5 more
core   +2 more sources

SARS-CoV-2 Neutralizing Antibodies: A Network Meta-Analysis across Vaccines

Vaccines, 2021
Background: There are no studies providing head-to-head comparison across SARS-CoV-2 vaccines. Therefore, we compared the efficacy of candidate vaccines in inducing neutralizing antibodies against SARS-CoV-2.
Paola Rogliani, Alfredo Chetta, Mario Cazzola, Luigino Calzetta   +3 more
doaj   +1 more source

Sterilization of lung matrices by supercritical carbon dioxide [PDF]

, 2016
Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L, Blatt, Kelly M S, Broekelmann, Tom J, Gard, Ashley L, Huie, Janet, Liu, Angela, Mecham, Robert P, Niklason, Laura E, Schwan, Jonas, Wilcox, Elise C, Zhao, Liping   +10 more
core   +2 more sources

Mycophenolate Mofetil Improves Exercise Tolerance in Systemic Sclerosis Patients with Interstitial Lung Disease: A Pilot Study

Rheumatology and Therapy, 2020
Introduction Systemic sclerosis (SSc) is an autoimmune disease characterized by the overproduction of collagen leading to fibrosis of the skin and internal organs.
Valentina Vaiarello, Stefano Schiavetto, Federica Foti, Antonietta Gigante, Francesco Iannazzo, Gregorino Paone, Paolo Palange, Edoardo Rosato   +7 more
doaj   +1 more source