Results 31 to 40 of about 1,239,389 (314)

The value of high-resolution computed tomography (HRCT) to determine exercise ventilatory inefficiency and dynamic hyperinflation in adult patients with cystic fibrosis

open access: yesRespiratory Research, 2019
Introduction In Cystic Fibrosis (CF), exercise ventilatory inefficiency and dynamic hyperinflation (DH) cause exercise limitation and induce poor exercise tolerance.
Ernesto Crisafulli   +12 more
doaj   +1 more source

Cardiac mechanics and reverse remodelling under mechanical support from left ventricular assist devices

open access: yesFrontiers in Cardiovascular Medicine, 2023
In recent years, development of mechanical circulatory support devices has proved to be a new treatment modality, in addition to standard pharmacological therapy, for patients with heart failure or acutely depressed cardiac function.
Blanca Pamias-Lopez   +3 more
doaj   +1 more source

Lung Function and Risk of Type 2 Diabetes and Fatal and Nonfatal Major Coronary Heart Disease Events: Possible Associations With Inflammation [PDF]

open access: yes, 2010
OBJECTIVE - We prospectively examined the relationship between lung function and risk of type-2 diabetes and fatal and nonfatal coronary heart disease (CHD) events and investigated the hypothesis that inflammation may underlie these associations ...
Lowe, G.D.   +20 more
core   +1 more source

Concurrent micro- to macro-cardiac electrophysiology in myocyte cultures and human heart slices

open access: yesScientific Reports, 2018
The contact cardiac electrogram is derived from the extracellular manifestation of cellular action potentials and cell-to-cell communication. It is used to guide catheter based clinical procedures.
Rasheda A. Chowdhury   +9 more
doaj   +1 more source

Severe acute respiratory failure due to a multifactorial diffuse alveolar haemorrhage

open access: yesRespirology Case Reports, 2020
Diffuse alveolar haemorrhage (DAH) is a life‐threatening syndrome caused by infection, coagulation disorders or autoimmune diseases. We here report the case of an 81‐year‐old male subject affected by a multifactorial DAH, in which the bleeding was ...
Ernesto Crisafulli   +4 more
doaj   +1 more source

Lung function in the general population : the complex interplay of variants in "Serpina1" and other genes with the environment [PDF]

open access: yes, 2013
Background. One of the globally most frequent health problems are obstructive lung diseases such as asthma and chronic obstructive pulmonary disease.
Thun, Gian Andri
core   +1 more source

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

open access: yesFrontiers in Physiology, 2018
Introduction: We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains.
Peter T. Wright   +9 more
doaj   +1 more source

Airway function at one year: association with premorbid airway function, wheezing, and maternal smoking [PDF]

open access: yes, 2001
Background - Impaired growth and development of the respiratory system during fetal and early postnatal life may have important implications for lung development and later lung health.
Wade, AM   +11 more
core   +1 more source

Ultrasound evaluation of diaphragmatic function in patients with idiopathic pulmonary fibrosis: a retrospective observational study

open access: yesRespiratory Research, 2023
Introduction The diaphragm function assessed by ultrasound has been well-studied in COPD, asthma, and intensive care. However, there are only a few studies on diffuse interstitial lung disease, while dyspnea and quality of life are major issues in the ...
Jules Milesi   +7 more
doaj   +1 more source

Integrated Bayesian approach to incorporate prior biological knowledge in the investigation of genetic variants associated with lung function [PDF]

open access: yes, 2018
Genetic association studies aim to identify single-nucleotide polymorphisms (SNPs) that are associated with complex diseases and traits. These studies, especially those performed at the genome-wide level, have successfully identified many SNPs associated
Pereira, M
core   +1 more source

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