Results 21 to 30 of about 1,159,013 (264)

Cardiac mechanics and reverse remodelling under mechanical support from left ventricular assist devices

Frontiers in Cardiovascular Medicine, 2023
In recent years, development of mechanical circulatory support devices has proved to be a new treatment modality, in addition to standard pharmacological therapy, for patients with heart failure or acutely depressed cardiac function.
Blanca Pamias-Lopez, Michael E. Ibrahim, Fotios G. Pitoulis, Fotios G. Pitoulis   +3 more
doaj   +1 more source

Concurrent micro- to macro-cardiac electrophysiology in myocyte cultures and human heart slices

Scientific Reports, 2018
The contact cardiac electrogram is derived from the extracellular manifestation of cellular action potentials and cell-to-cell communication. It is used to guide catheter based clinical procedures.
Rasheda A. Chowdhury, Konstantinos N. Tzortzis, Emmanuel Dupont, Shaun Selvadurai, Filippo Perbellini, Chris D. Cantwell, Fu Siong Ng, Andre R. Simon, Cesare M. Terracciano, Nicholas S. Peters   +9 more
doaj   +1 more source

Severe acute respiratory failure due to a multifactorial diffuse alveolar haemorrhage

Respirology Case Reports, 2020
Diffuse alveolar haemorrhage (DAH) is a life‐threatening syndrome caused by infection, coagulation disorders or autoimmune diseases. We here report the case of an 81‐year‐old male subject affected by a multifactorial DAH, in which the bleeding was ...
Ernesto Crisafulli, Barbara Burgazzi, Maria Majori, Walter Serra, Alfredo Chetta   +4 more
doaj   +1 more source

Partial Mechanical Unloading of the Heart Disrupts L-Type Calcium Channel and Beta-Adrenoceptor Signaling Microdomains

Frontiers in Physiology, 2018
Introduction: We investigated the effect of partial mechanical unloading (PMU) of the heart on the physiology of calcium and beta-adrenoceptor-cAMP (βAR-cAMP) microdomains.
Peter T. Wright, Jose L. Sanchez-Alonso, Carla Lucarelli, Carla Lucarelli, Anita Alvarez-Laviada, Claire E. Poulet, Sean O. Bello, Giuseppe Faggian, Cesare M. Terracciano, Julia Gorelik   +9 more
doaj   +1 more source

Ultrasound evaluation of diaphragmatic function in patients with idiopathic pulmonary fibrosis: a retrospective observational study

Respiratory Research, 2023
Introduction The diaphragm function assessed by ultrasound has been well-studied in COPD, asthma, and intensive care. However, there are only a few studies on diffuse interstitial lung disease, while dyspnea and quality of life are major issues in the ...
Jules Milesi, Alain Boussuges, Paul Habert, Julien Bermudez, Martine Reynaud-Gaubert, Stéphane Delliaux, Fabienne Bregeon, Benjamin Coiffard   +7 more
doaj   +1 more source

SARS-CoV-2 Neutralizing Antibodies: A Network Meta-Analysis across Vaccines

Vaccines, 2021
Background: There are no studies providing head-to-head comparison across SARS-CoV-2 vaccines. Therefore, we compared the efficacy of candidate vaccines in inducing neutralizing antibodies against SARS-CoV-2.
Paola Rogliani, Alfredo Chetta, Mario Cazzola, Luigino Calzetta   +3 more
doaj   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Distinct phenotype and risk factor analysis of persistent airflow limitation among asthmatic children: a case-control study

BMC Pediatrics
Background Persistent airflow limitation (PAL) in childhood asthma is associated with a poor prognosis. The aim of this study was to categorize asthmatic children with PAL into distinct phenotypes and investigate the risk factors associated with each ...
Shiqiu Xiong, Xinyu Jia, Wei Chen, Chuanhe Liu   +3 more
doaj   +1 more source

Mycophenolate Mofetil Improves Exercise Tolerance in Systemic Sclerosis Patients with Interstitial Lung Disease: A Pilot Study

Rheumatology and Therapy, 2020
Introduction Systemic sclerosis (SSc) is an autoimmune disease characterized by the overproduction of collagen leading to fibrosis of the skin and internal organs.
Valentina Vaiarello, Stefano Schiavetto, Federica Foti, Antonietta Gigante, Francesco Iannazzo, Gregorino Paone, Paolo Palange, Edoardo Rosato   +7 more
doaj   +1 more source

Guidelines for Pediatric Radiotherapy Simulation: A Report From the Children's Oncology Group Radiation Oncology Discipline

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei, Stephen Mihalcik, Sujith Baliga, Young Kwok, Dana Casey, Eric Ehler, Christiane Burton, John C. Breneman, Daphne A. Haas‐Kogan, Suzanne L. Wolden, Arnold C. Paulino, Nadia N. Laack, Natia Esiashvili, Sarah Milgrom, Christine Hill‐Kayser, Thomas J. Fitzgerald, John A. Kalapurakal, Chia‐Ho Hua   +17 more
wiley   +1 more source