Muscles and lungs: fatal attraction, but time for intervention
Monaldi Archives for Chest Disease, 2005 -
J.C. Winck, M. Gonçalves
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Clinical manifestations of a new alpha‐1 antitrypsin genetic variant: Q0parma
Respirology Case Reports, 2022 Alpha‐1 antitrypsin deficiency is an autosomal, codominant disorder caused by mutations of the SERPINA1 gene. Several mutations of SERPINA1 have been described associated with the development of pulmonary emphysema and/or chronic liver disease and ...
Marina Aiello +9 more
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Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma
Biomedicines, 2022 Inhaled corticosteroids (ICS) remain the mainstay of asthma treatment, along with bronchodilators serving as control agents in combination with ICS or reliever therapy.
Luigino Calzetta +6 more
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Quantitative CT analysis in patients with pulmonary emphysema: is lung function influenced by concomitant unspecific pulmonary fibrosis? [PDF]
, 2019 Purpose: Quantitative analysis of CT scans has proven to be a reproducible technique, which might help to understand the pathophysiology of chronic obstructive pulmonary disease (COPD) and combined pulmonary fibrosis and emphysema.
Doellinger, Felix +5 more
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Cells, 2022 COPD is an incurable disorder, characterized by a progressive alveolar tissue destruction and defective mechanisms of repair and defense leading to emphysema.
Luigino Calzetta +6 more
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Pharmaceutics, 2022 Despite females being more often affected by asthma than males and the prevalence of COPD rising in females, conflicting evidence exists as to whether sex may modulate the correct inhaler technique.
Luigino Calzetta +6 more
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Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation [PDF]
, 2011 Deficiency of vitamin D is associated with accelerated decline in lung function. Vitamin D is a ligand for nuclear hormone vitamin D receptor (VDR), and upon binding it modulates various cellular functions.
Hwang, Jae-woong +4 more
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Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency. [PDF]
, 2015 Adenosine deaminase-deficient severe combined immunodeficiency (ADA-SCID) is characterized by impaired T-, B- and NK-cell function. Affected children, in addition to early onset of infections, manifest non-immunologic symptoms including pulmonary ...
Candotti, Fabio +6 more
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Improving spirometry testing by understanding patient preferences
ERJ Open Research, 2021 The American Thoracic Society and European Respiratory Society commissioned a task force to update the technical standards for spirometry testing with the aim of increasing the accuracy, precision and quality of spirometry measurements and improving the ...
Barbara Johnson +3 more
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Lung function after prolonged lung preservation
The Journal of Thoracic and Cardiovascular Surgery, 1989 Our previous study revealed significant improvement in lung preservation with a new solution, the UCLA formula, which contains verapamil and is based on a glucose-insulin-potassium solution. In this study, we extended the preservation time up to 12 hours and, using various parameters, compared lung function after 12 hours' preservation with that after ...
M, Hachida, D L, Morton
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