Results 11 to 20 of about 1,239,389 (314)

Muscles and lungs: fatal attraction, but time for intervention

open access: yesMonaldi Archives for Chest Disease, 2005
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J.C. Winck, M. Gonçalves
doaj   +1 more source

Early life origins of lung ageing : early life exposures and lung function decline in adulthood in two European cohorts aged 28-73 years [PDF]

open access: yes, 2015
Early life environment is essential for lung growth and maximally attained lung function. Whether early life exposures impact on lung function decline in adulthood, an indicator of lung ageing, has scarcely been studied.; Spirometry data from two time ...
Svanes, C.   +123 more
core   +1 more source

The association between blood coagulation activity and lung function: a population-based study [PDF]

open access: yes, 2010
<p><b>Background:</b> Increased in susceptibility to thrombotic disease may be associated with lower lung function. If causal, this association may suggest an area for development of new interventions for lung disease.
Lowe, G.D.O.   +16 more
core   +1 more source

Different genes interact with particulate matter and tobacco smoke exposure in affecting lung function decline in the general population [PDF]

open access: yes, 2012
BACKGROUND: Oxidative stress related genes modify the effects of ambient air pollution or tobacco smoking on lung function decline. The impact of interactions might be substantial, but previous studies mostly focused on main effects of single genes ...
Russi, Erich W.   +76 more
core   +1 more source

Clinical manifestations of a new alpha‐1 antitrypsin genetic variant: Q0parma

open access: yesRespirology Case Reports, 2022
Alpha‐1 antitrypsin deficiency is an autosomal, codominant disorder caused by mutations of the SERPINA1 gene. Several mutations of SERPINA1 have been described associated with the development of pulmonary emphysema and/or chronic liver disease and ...
Marina Aiello   +9 more
doaj   +1 more source

Investigational Treatments in Phase I and II Clinical Trials: A Systematic Review in Asthma

open access: yesBiomedicines, 2022
Inhaled corticosteroids (ICS) remain the mainstay of asthma treatment, along with bronchodilators serving as control agents in combination with ICS or reliever therapy.
Luigino Calzetta   +6 more
doaj   +1 more source

Stem Cell-Based Regenerative Therapy and Derived Products in COPD: A Systematic Review and Meta-Analysis

open access: yesCells, 2022
COPD is an incurable disorder, characterized by a progressive alveolar tissue destruction and defective mechanisms of repair and defense leading to emphysema.
Luigino Calzetta   +6 more
doaj   +1 more source

Large-Scale Genome-Wide Association Studies and Meta-Analyses of Longitudinal Change in Adult Lung Function [PDF]

open access: yes, 2014
Background: Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.
Wenbo Tang (110161)   +616 more
core   +1 more source

Impact of Sex on Proper Use of Inhaler Devices in Asthma and COPD: A Systematic Review and Meta-Analysis

open access: yesPharmaceutics, 2022
Despite females being more often affected by asthma than males and the prevalence of COPD rising in females, conflicting evidence exists as to whether sex may modulate the correct inhaler technique.
Luigino Calzetta   +6 more
doaj   +1 more source

Acute and short-term effects of secondhand smoke on lung function and cytokine production. [PDF]

open access: yes, 2009
RATIONALE: The acute effect of secondhand smoke (SHS) on lung function and the duration of system disruption remain unknown. OBJECTIVES: To assess the SHS effects and their duration on lung function and inflammatory markers.
Metsios, Giorgos S.   +13 more
core   +1 more source

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