Results 141 to 150 of about 42,166 (258)

Effects of inhaled bronchodilators on dynamic lung mechanics during exercise in COPD: protocol for a randomised, placebo-controlled crossover trial. [PDF]

ERJ Open Res
Alosta K, James MD, Vincent SG, Smyth RM, Hijleh AA, Back GD, Porcella A, Domnik NJ, O'Donnell DE, Neder JA.   +9 more
europepmc   +1 more source

Human‐Scale Rotating Magnetic Field Delivery With Permanent Magnets Under Anatomic and Robotic Constraints

Advanced Robotics Research, EarlyView.
Rotating magnetic fields (RMFs) are widely used for microrobot propulsion and control. We show that RMF generation with permanent magnets is mechanically feasible for many limb and intracranial applications but becomes constrained for thoracic targets.
Tuan‐Anh Le, Husnu Halid Alabay, Anika Sivarasa, Gia‐Minh Hoang, Hakan Ceylan   +4 more
wiley   +1 more source

Two Physiologic Latent Classes of Acute Hypoxemic Respiratory Failure in Sepsis Are Distinguished by Lung Mechanics and Gas Exchange. [PDF]

Crit Care Explor
Bennett RM, Housel KC, Jones TK, Giannini HM, Emre G, Esperanza M, Turner A, Ittner C, Shashaty MGS, Feng R, Anderson MR, Weissman GE, Meyer NJ, Christie JD, Reilly JP.   +14 more
europepmc   +1 more source

Lung Mechanics of the Obese Undergoing Robotic Surgery and the Pursuit of Protective Ventilation. [PDF]

Anesthesiology, 2020
Bao X, Vidal Melo MF.
europepmc   +1 more source

Inspiratory Effort and Lung Mechanics in Spontaneously Breathing Patients with Acute Respiratory Failure due to COVID-19: A Matched Control Study. [PDF]

Am J Respir Crit Care Med, 2021
Tonelli R, Busani S, Tabbì L, Fantini R, Castaniere I, Biagioni E, Mussini C, Girardis M, Clini E, Marchioni A.   +9 more
europepmc   +1 more source

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

Advanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez, Rose E. Presby, Sara Nakanishi, Pallavi Gaur, Ugur Akcan, Johannes Daugaard Krog, Iben Daugaard Krog, Lipi Das, David S. Johnson, Danny Jamoul, Douglas Jury, Brian Lawson, Jacob Körbelin, Lewis M. Brown, Vilas Menon, Dritan Agalliu, Irene Munk Pedersen   +16 more
wiley   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

Fibrotic and emphysematous murine lung mechanics under negative-pressure ventilation. [PDF]

Am J Physiol Lung Cell Mol Physiol
Quiros KAM, Nelson TM, Ulu A, Dominguez EC, Nordgren TM, Eskandari M.   +5 more
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Associations Between Esophageal Motility, Reflux, and Lung Mechanics and Function Are Disease-Specific, Both Between and Within Restrictive and Obstructive Lung Disease. [PDF]

Clin Transl Gastroenterol
Alghubari A, Olson C, Bradley J, Cheah R, Shah SZ, Naser AN, Lee AS, DeVault KR, Houghton LA.   +8 more
europepmc   +1 more source