Results 201 to 210 of about 612,549 (305)

Tumor neoantigen gene C7orf50 remodels the immune microenvironment by recruiting tumor-associated macrophages to promote hepatocellular carcinoma progression and lung metastasis. [PDF]

J Immunother Cancer
Li J, Ye X, Su S, Hu Z, Chen C, Gong Y, Li Z, Qi F, Li H, Mao L, Huang X.   +10 more
europepmc   +1 more source

Cancer Cells Traverse Faster in Confined Space by Modifying Vimentin filaments With Nuclear Deformation and Promoting the Growth of Desired Tumor Spheroids

Advanced Materials Interfaces, EarlyView.
This study demonstrates how the Vimentin intermediate (VIM) filaments distribution/density regulates the attainment of different migration modes through cytoskeleton rearrangement and controls the nuclear morphology in migrating cells under physical confinement, which facilitates the faster traversing of those cells and the growth of post‐migration ...
Md Kowsar Alam, Jiao Zhai, Heng Zou, Yu Chen, Michael Yang   +4 more
wiley   +1 more source

Biomimetic PD-1-nanovesicles inducing tri-modal sonodynamic-chemo-immunotherapy for breast cancer therapy and lung metastasis inhibition. [PDF]

J Nanobiotechnology
Lin W, Lin Z, Fu F, Li Z, Dong H, Liu L, Xie X, Zhang X.   +7 more
europepmc   +1 more source

Multiplexed Luminal Tissue Constructs with Reconfigurable Barriers for Dynamic Modeling of Multi‐Tissue Interactions

Advanced Materials Technologies, EarlyView.
This study describes the fabrication of arrays of luminal tissue constructs for 3D luminal tissue modeling. An oil or media‐filled reservoir between constructs serves as a liquid barrier or bridge to regulate communication between lumens within the array for modeling multi‐tissue interactions in vitro. Abstract Cell‐lined luminal structures are crucial
Mouhita Humayun, José A. Jiménez‐Torres, Chao Li, Jose M. Ayuso, Karina Lugo‐Cintron, Joseph Ulbrich, Benjamin Myers, Sheena C. Kerr, Adeel Ahmed, David J. Beebe   +9 more
wiley   +1 more source

Protocol for isolation and flow cytometric analysis of interstitial macrophages in murine lung metastasis models. [PDF]

STAR Protoc
Jeong MR, Seok SH.
europepmc   +1 more source

Inhibition of tumor–microenvironment interaction and tumor invasion by small-molecule allosteric inhibitor of DDR2 extracellular domain [PDF]

, 2018
Grither, Whitney R., Longmore, Gregory D.   +1 more
core   +1 more source

Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems

Advanced Materials Technologies, EarlyView.
Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley   +1 more source

Case Report: Pulmonary enteric adenocarcinoma harboring KRAS/TP53/APC mutations with contralateral lung metastasis: diagnostic challenges and molecular insights. [PDF]

Front Oncol
Mao M, Hu M, Tao Q, Zuo Z, Liu B.
europepmc   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

Advanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang, He Huang, Hongliang Dong, Qiang Ma, Hongyan Jin   +4 more
wiley   +1 more source

Magnetic hyperthermia using iron oxide nanoparticles via LDDS suppressed lymph node and lung metastasis in a mouse model. [PDF]

Sci Rep
Kuwahata A, Sukhbaatar A, Shikano A, Tonthat L, Kagami T, Shinohara R, Mori S, Yabukami S, Kodama T.   +8 more
europepmc   +1 more source