Results 251 to 260 of about 612,549 (305)

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

open access: yesAdvanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang   +16 more
wiley   +1 more source

A Case of Cavitary Lung Metastasis From Prostate Cancer. [PDF]

open access: yesRespirol Case Rep
Ohnaka S   +10 more
europepmc   +1 more source

Lipid nanoparticle-delivered IFNα2 activates Cxcl9 to increase T cell tumor recruitment to suppress lung metastasis. [PDF]

open access: yesJ Immunother Cancer
Fick K   +13 more
europepmc   +1 more source

Modeling Ewing Sarcoma Lung Metastasis

Current Protocols, 2023
AbstractEwing Sarcoma (EwS) is the second most common malignant bone tumor in adolescents and young adults. The single‐most powerful predictor of outcome in EwS is presence of metastatic burden at the time of diagnosis. Patients with metastatic Ewing Sarcoma have an abysmal 5‐year survival rate of 10%‐25%, which has not changed over the past 30‐40 ...
Dasgupta, Atreyi   +7 more
openaire   +3 more sources

Lung metastasis of a meningioma

Neuroradiology, 1983
Case report of a 35-year-old male patient. 1976: operation for a falx-meningioma. 1981: meningioma recurrence and further intracranial meningiomas.1976 and 1981 endotheliomatous meningioma: no signs of malignancy. Prior to the 2nd operation in 1981 a lung tumor was diagnosed for the first time.
S, Wende   +3 more
openaire   +2 more sources

Splenic metastasis from lung cancer

The Netherlands Journal of Medicine, 1995
Splenic metastasis from lung cancer is a rare clinical event, most often diagnosed at the time of autopsy. We report 2 cases of splenic metastasis with a primary lung cancer. The first case was a 76-year-old man presenting with a recurrent solitary splenic metastasis 14 months after surgical removal of a squamous cell carcinoma of the lung.
A, Kinoshita   +9 more
openaire   +2 more sources

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