Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
PRMT1-Mediated PARP1 Methylation Drives Lung Metastasis and Chemoresistance via P65 Activation in Triple-Negative Breast Cancer. [PDF]
Zhang J +9 more
europepmc +1 more source
A Case of Cavitary Lung Metastasis From Prostate Cancer. [PDF]
Ohnaka S +10 more
europepmc +1 more source
A Decade-long Battle: Successful Stereotactic Radiotherapy for a Delayed Lung Metastasis from Endometrial Cancer. [PDF]
Hama Y, Tate E.
europepmc +1 more source
Impact of cancer-directed surgery for gastric cancer patients with lung metastasis: a prognosis analysis. [PDF]
Tan Z +5 more
europepmc +1 more source
Lipid nanoparticle-delivered IFNα2 activates Cxcl9 to increase T cell tumor recruitment to suppress lung metastasis. [PDF]
Fick K +13 more
europepmc +1 more source
ZWINT down-regulated by miR-495-3p inhibited lung metastasis of breast cancer by blocking p38 MAPK signaling pathway activation. [PDF]
Shao MT +9 more
europepmc +1 more source
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