Results 121 to 130 of about 971,492 (311)

Cancer‐Associated Fibroblasts Promote Glucose Metabolic Reprogramming and Progression of Triple‐Negative Breast Cancer via Exosomal circFAD104‐Mediated Intercellular Communication

Advanced Science, EarlyView.
CAF‐derived exosomes deliver circFAD104 into TNBC cells, where it acts as a molecular scaffold that bridges the E3 ligase MARCHF8 and PGM1, promoting MARCHF8‐mediated K48‐linked ubiquitination and proteasomal degradation of PGM1. Loss of PGM1 redirects glucose‐phosphate flux from glycogen synthesis toward glycolysis, thereby driving stemness, EMT, and ...
Lei Wang, Xiaoyan Li, Yiran Liang, Yifei Wang, Yuhan Jin, Jianing Wang, Dan Luo, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Wenjing Zhao, Bing Chen, Lijuan Wang, Qifeng Yang   +16 more
wiley   +1 more source

Lung nodule malignancy classification with associated pulmonary fibrosis using 3D attention-gated convolutional network with CT scans

Journal of Translational Medicine
Background Chest Computed tomography (CT) scans detect lung nodules and assess pulmonary fibrosis. While pulmonary fibrosis indicates increased lung cancer risk, current clinical practice characterizes nodule risk of malignancy based on nodule size and ...
Yucheng Liu, Hao Yun Hsu, Tiffany Lin, Boyu Peng, Anjali Saqi, Mary M. Salvatore, Sachin Jambawalikar   +6 more
doaj   +1 more source

Lung Nodule Detection In Ct Scans

, 2004
In this paper we describe a computer-aided diagnosis (CAD) system for automated detection of pulmonary nodules in computed-tomography (CT) images. After extracting the pulmonary parenchyma using a combination of image processing techniques, a region growing method is applied to detect nodules based on 3D geometric features. We applied the CAD system to
ANTONELLI, MICHELA, FROSINI, GRAZIANO, LAZZERINI, BEATRICE, MARCELLONI, FRANCESCO   +3 more
openaire   +4 more sources

Generated 2D lung nodules

This is the generated 2D lung nodule dataset used in the paper “HIA-DDP: Hard-Instance-Aware Dynamic Data Pruning with Diffusion-based Augmentation and Knowledge-Prior Guidance for 2D/3D Lung Nodule Segmentation.
Zhang, Siqin
core   +1 more source

Force‐Electric Nanotentacles of Tantalum Implant Accelerate Cellular Energy Metabolism/Crosstalk for Immunomodulation‐Vascularized Bone Integration

Advanced Science, EarlyView.
A biomimetic force‐electric nanotentacle‐enabled tantalum (Ta) implant with surface‐nanostructured LiTaO3 (n‐LiTaO3) was first developed via laser nanofabrication combined with Li+‐induced in situ reaction, enabling the transduction of ultrasound into bioelectrical cues.
Taixing Zhang, Ke Ma, Kangqing Zuo, Pandong Lin, Tailong Zhang, Rongliang Ding, Linbo Zhang, Aonan Li, Yinchuan Wang, Yanling Huang, Jichao Feng, Guiyong Xiao, Yupeng Lu, Bing Han, Zhiqiang Wang, Ningbo Li   +15 more
wiley   +1 more source

Pulmonary Nodule Segmentation Using Deep Learning: A Review

IEEE Access
Accurate segmentation of pulmonary nodule within medical imagery is of great significance for classification and diagnosis. This task is profoundly challenging due to scarcity of annotated data, the diversity of lung nodule features, and the complexity ...
Yong Wang, Seri Mastura Mustaza, Mohammad Syuhaimi Ab-Rahman   +2 more
doaj   +1 more source

Nodule detection sensitivity of Lung VCAR.

PurposeTo prospectively evaluate whether Lung-RADS classification and volumetric nodule assessment were feasible with ultralow-dose (ULD) chest CT scans with deep learning image reconstruction (DLIR).MethodsThe institutional review board approved this ...
Soon Ho Yoon (5778260), Hyewon Choi (687527), Seung-Jin Yoo (2983260), Jin Mo Goo (8727549), Da Som Kim (5486057), Young Sik Park (11614169)   +5 more
core   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

Advanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao, Zunlei Gong, Chuke Chen, Hui Yu, Yu Cai, Can Liu, Hongkai Huang, Ying Li, Jinyuan Guan, Le Wang, Chengyun Ning, Guoxin Tan, Lei Zhou   +12 more
wiley   +1 more source

Pulmonary Langerhans Cell Histiocytosis: An Unusual Differential for a Solitary Lung Nodule

Case Reports in Pulmonology
Background. Pulmonary Langerhans cell histiocytosis (LCH) commonly presents as bilateral reticulonodular and cystic lung changes on chest imaging. Isolated lung nodule presentation is rare. Case Presentation. Our patient was an elderly male and an active
Tessabella M. Magliochetti Cammarata, Sushan Gupta, Sai Sri Harsha Rallabhandi, Vishesh Paul   +3 more
doaj   +1 more source

Computed Tomography Perfusion Using First Pass Methods for Lung Nodule Characterization: Limits and Implications in Radiologic Practice

, 2009
Computed tomography perfusion using first pass methods for lung nodule ...
MAZZEI M. A., VOLTERRANI L., SCIALPI M., FEDI M.   +3 more
core   +1 more source