Results 61 to 70 of about 900,764 (306)

Photoacoustic Nanotagging for In Vivo Tracking and Optimization of Macrophage Immunotherapy in Solid Tumors

Advanced Materials, EarlyView.
Macrophage‐based immunotherapy for solid tumors is limited by poor tracking of cell localization and persistence. This study introduces nanotagged macrophages enabling near‐infrared photoacoustic imaging for real‐time monitoring. IFNγ‐conjugated tags enhance antitumor polarization without harming viability.
Seoyoon Song, Melissa Cadena, Myeongsoo Kim, Euisuk Chung, Jeungyoon Lee, Zlata Brushevich, Seonghun Shin, Paul S. Pelkowski, Stanislav Y. Emelianov   +8 more
wiley   +1 more source

Artificial intelligence in lung cancer screening: Detection, classification, prediction, and prognosis

Cancer Medicine
Background The exceptional capabilities of artificial intelligence (AI) in extracting image information and processing complex models have led to its recognition across various medical fields.
Wu Quanyang, Huang Yao, Wang Sicong, Qi Linlin, Zhang Zewei, Hou Donghui, Li Hongjia, Zhao Shijun   +7 more
doaj   +1 more source

Impact of Deep Learning 3D CT Super-Resolution on AI-Based Pulmonary Nodule Characterization

Tomography
Background/Objectives: Correct pulmonary nodule volumetry and categorization is paramount for accurate diagnosis in lung cancer screening programs. CT scanners with slice thicknesses of multiple millimetres are still common worldwide, and slice thickness
Dongok Kim, Chulkyun Ahn, Jong Hyo Kim
doaj   +1 more source

Correlation between lung cancer probability and number of pulmonary nodules in baseline computed tomography lung cancer screening: A retrospective study based on the Chinese population

Frontiers in Oncology, 2023
BackgroundScreening for lung cancer with LDCT detects a large number of nodules. However, it is unclear whether nodule number influences lung cancer probability.
Quanyang Wu, Shijun Zhao, Yao Huang, Jianwei Wang, Wei Tang, Lina Zhou, Linlin Qi, Zewei Zhang, Yuting Xie, Jiaxing Zhang, Hongjia Li, Ning Wu, Ning Wu   +12 more
doaj   +1 more source

Crowdsourcing lung nodules detection and annotation [PDF]

Medical Imaging 2018: Imaging Informatics for Healthcare, Research, and Applications, 2018
7 pages, SPIE Medical Imaging ...
Saeed Boorboor, Saad Nadeem, Ji Hwan Park, Kevin Baker, Arie E. Kaufman   +4 more
openaire   +3 more sources

NIR‐II Light‐Triggered Electron Flow Initiates Cuproptosis‐Centered Thermoelectric‐Immunotherapy for Breast Cancer

Advanced Science, EarlyView.
A NIR‐II light‐activatable thermoelectric nanoreactor converts surface‐bound Cu2+ into bioactive Cu+ via directed electron flow. This spatiotemporally controlled reduction triggers potent cuproptosis and immunogenic cell death, eradicating primary tumors and, together with aPD‐1 therapy, suppressing metastases while establishing durable immune memory ...
Boyu Yuan, Qin Fan, Shushu Chu, Shining Yang, Yuechao Yang, Chenxi Zhang, Jinqiao Zhang, Xinran Qu, Yiju Wei, Xin Wang, Ziliang Dong   +10 more
wiley   +1 more source

Lung Nodules Segmentation with DeepHealth Toolkit

, 2022
Abstract. The accurate and consistent border segmentation plays an important role in the tumor volume estimation and its treatment in the field of Medical Image Segmentation. Globally, Lung cancer is one of the leading causes of death and the early detection of lung nodules is essential for the early cancer diagnosis and survival rate of patients.
Hafiza Ayesha Hoor Chaudhry, Riccardo Renzulli, Daniele Perlo, Francesca Santinelli, Stefano Tibaldi, Carmen Cristiano, Marco Grosso, Attilio Fiandrotti, Maurizio Lucenteforte, Davide Cavagnino   +9 more
openaire   +4 more sources

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

Advanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta, Shuyi Wang, Boyan Zhang, Ning Liu, Yingchen Han, Aoran Liu, Ying Xu, Tingsong Chen, Ye Zhang, Qiuhua Luo, Tao Han   +10 more
wiley   +1 more source

ANXA2+ Small Extracellular Vesicles Drive Chemoresistance in Anaplastic Thyroid Cancer by Promoting XRCC5 Lactylation and Enhancing Non‐Homologous End‐Joining Repair

Advanced Science, EarlyView.
ANXA2+ sEVs promote cisplatin resistance in ATC by stabilizing the SRC/LDHA interaction, increasing LDHA phosphorylation and activity, and lactate production. Elevated lactate levels promote KAT5‐mediated lactylation of XRCC5 at lysine 265, enhancing its binding to XRCC6.
Shanshan Su, YiShan Xiong, Yuxuan Liang, Xiang Min, Daofeng Dai   +4 more
wiley   +1 more source

Polymetallic nodule mining: innovative concepts for commercialisation

, 2012
Seabed resources of value to the modern economy include oil and gas reserves, placerdeposits including diamonds and gold, and minerals found in the form of Seafloor MassiveSulfides, Sediments, Crusts and Polymetallic (Manganese) Nodules.A review of the ...
Lee, Sang Eui, Zabeen, Suraiya, Wang, Shiping, Virnovskaia, Anastasia, Flentje, Warren   +4 more
core   +1 more source