Results 81 to 90 of about 900,764 (306)

3D V-Net Detection of Pulmonary Nodules with Integrated Attention Mechanisms

Journal of Harbin University of Science and Technology
Lung nodules play a crucial role in the early diagnosis and treatment of lung cancer. To address the existing issues of missed and false detections in current lung nodule detection algorithms, we propose a 3DV-Net model that incorporates an attention ...
WEI Haiyue, CHEN Hailong, XU Xinyao, ZHANG Xiuxia, ZHOU Xinpeng   +4 more
doaj   +1 more source

Variable radiological lung nodule evaluation leads to divergent management recommendations

, 2018
: Radiological evaluation of incidentally detected lung nodules on computed tomography (CT) influences management. We assessed international radiological variation in 1) pulmonary nodule characterisation; 2) hypothetical guideline-derived management; and
Hoesein, Firdaus A. Mohamed, Maidas, Panagiotis, Nganga, Edward, Desai, Sujal R., Eberhard, Matthias, Grgic, Aleksandar, Benes, Jiri, Jr., Dalpiaz, Giorgia, Oikonomou, Anastasia, Farchione, Alessandra, Haramati, Linda, Tomiyama, Noriyuki, Roos, Justus, Klein, Jeffrey S., Bozovic, Gracijela, De Jong, Pim A., Mariani, Francesca, Gavelli, Giampaolo, Pope, Kristen, Kanne, Jeffrey, Thi Dan Linh Nguyen-Kim, Rossi, Santiago, Pulzato, Ilaria, Romei, Chiara, Nath, Hrudaya, Nair, Arjun, Bartlett, Emily C., Munoz Nunez, Carlos Francisco, Silva, Mario, Villanueva, Alberto, Schaefer-Prokop, C. M., Iiartman, Thomas, Kapur, Sangita, Sverzellati, Nicola, Escuissato, Dante, Behr, Julien, Ip, Joana, Meirelles, Gustavo, Navani, Neal, Hering, Jan Philipp, Kul, Melahat, Rampinelli, Cristiano, Santos, Marcel Koenigkam, Pandher, Tej, Johnson, Katharine, Frauenfelder, Thomas, Snoeckx, Annemie, Romanos, Odyssefs, Chaves, Marcelo, Fujimoto, Kiminori, Poerio, Antonio, Hobbs, Susan, Kirova, Galina, Herpels, Vincent, Taydas, Onur, Ko, Jane, Sonavane, Sushilkumar, David, Sarojini, Walsh, Simon L. F., Parkar, Anagha P., Gatti, Marco, Murchison, John, Dournes, Gad, Hursoy, Nur, Senbanjo, Taiwo, Piciucchi, Sara, Bhalla, Sanjeev, Kramer, Gerdien, Occhipiniti, Mariaelena, Williams, Michelle, Haine, Louise, Iyengar, Srikanth, Hartmann, Ieneke, Karaman, Can Zafer, Polverosi, Roberta, Ahlfors, Fredrik, Bastos, Andrea, Calandriello, Lucio, Wells, Athol U., Sanchez, Marcelo, Tran, Sa, Arenas Jimenez, Juan, Karl, Robert, Lee, Youkyung, Goo, Jin Mo, Schubert, Michael, Castaner, Eva, Herraez, Inmaculada, Choi, Yo Won, Rodrigues, Jonathan, Franchi, Paola, Stefanidis, Konstantinos, Hochhegger, Bruno, Larici, Anna Rita, Nenkina, Tatyana, Mak, Sze Mun, Ozawa, Yoshiyuki, Silva, Claudio, Prosch, Helmut, Machnicki, Stephen, Ley, Sebastian, Ruhtsov, Roman, Buzan, Maria Teodora, Flors, Lucia, Niemann, Tilo, Seo, Joon-Beom, Leifels, Leonard, Sriharan, Mona, Pinheiro, Diogo, MacMahon, Heber, Ruggirello, Margherita, Hardavella, Georgia, Devaraj, Anand, Montet, Xavier   +113 more
core  

Image_1_v1_Fluorescence-guided lung nodule identification during minimally invasive lung resections.jpeg

, 2022
In the last few years, minimally invasive surgery has become the standard routine practice to manage lung nodules. Particularly in the case of robotic thoracic surgery, the identification of the lung nodules that do not surface on the visceral pleura ...
Daniele Forcella (13108896), Enrico Melis (11447051), Paolo Visca (211495), Filippo Tommaso Gallina (13108893), Giulio Eugenio Vallati (13108899), Federico Pierconti (54699), Federico Cappelli (13108902), Francesco Facciolo (259657), Riccardo Tajè (13108890)   +8 more
core   +1 more source

Microprotein MP104 Promotes Malignant Progression of Colorectal Cancer Through Regulating Protein Translation

Advanced Science, EarlyView.
A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen, Miao Wang, Hongmei Yong, Jin Ding, Shiping Xu, Qirui Ge, Yan Wang, Lei Zhang, Qianqian Xiao, Benli Li, Li Lin, Sufang Chu, Qianqing Wang, Jin Bai, Pingfu Hou   +14 more
wiley   +1 more source

WDR72 Promotes Neuroblastoma Stemness and Progression by Sequestering TRIM31‐Mediated Degradation of CBX8

Advanced Science, EarlyView.
This study unveiled that METTL14 mediates m6A modification of WDR72 mRNA to stabilize and enhance WDR72 expression, which disrupts TRIM31‐mediated ubiquitination of CBX8 protein and retards its degradation, finally the elevated CBX8 contributes to tumor stemness.
Huijuan Zeng, Zijie Ye, Manna Zheng, Jing Pan, Tianbao Tan, Jiliang Yang, Jiahao Li, Zhang Zhao, Tianzhu Long, Liyu Zhang, Gautam Sethi, Tianyou Yang, Chao Hu, Yan Zou   +13 more
wiley   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

When A Lung Nodule is not the Usual Lung Nodule: the Rare Entity of PEComa

Journal of Respiratory Research, 2018
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Flavio Colaut, Nicola Clemente, Maurizio De Luca   +2 more
openaire   +3 more sources

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

Small Cell Lung Cancer in a Young, Non-Smoker Patient

Albanian Journal of Trauma and Emergency Surgery
Introduction: A single lung nodule (SPN) is defined as a solitary lung opacification less than 3 cm in size. In particular, small cell lung cancer (SCLC) affects more patients, older and heavy smokers.
Jolanda Nikolla, Daniela Xhemalaj, Arben Dhima, Daniela Bega   +3 more
doaj   +1 more source

A Programmable Calcification Nanoplatform for Loco‐Regional Calcification‐Immune Hepatocellular Carcinoma Therapy

Advanced Science, EarlyView.
An in situ‐grown BP‐CaO2 nanoplatform supplies coordinated Ca2+, endogenous phosphate, and oxidative stress to convert tumor calcification from a passive endpoint into an active immune‐remodeling process. Widespread hydroxyapatite deposition is visualized by CT, while multi‐omics reveals MCOLN2 as a calcium‐responsive mediator linking biomineralization
Long Liu, Peng Li, Zhixiang Lu, Shuqin Xu, Juanjuan Wang, Kai Ma, Haodong Yu, Can Zhou, Hu Chen, Gang Liu, Yi Lyu, Shuang Bai   +11 more
wiley   +1 more source