Results 1 to 10 of about 802,787 (231)

Intracranial response to positive end-expiratory pressure is influenced by lung recruitability and gas distribution during mechanical ventilation in acute brain injury patients: a proof-of-concept physiological study [PDF]

Intensive Care Medicine Experimental
Background The effect of positive end-expiratory pressure (PEEP) on intracranial pressure (ICP) dynamics in patients with acute brain injury (ABI) remains controversial. PEEP can benefit oxygenation by promoting alveolar recruitment, but its influence on
Reka Bencze, Rafael Kawati, Anders Hånell, Anders Lewen, Per Enblad, Henrik Engquist, Kristin Jona Bjarnadottir, Odin Joensen, Annelie Barrueta Tenhunen, Filip Freden, Laurent Brochard, Gaetano Perchiazzi, Mariangela Pellegrini   +12 more
doaj   +4 more sources

Radiological pattern in ARDS patients: partitioned respiratory mechanics, gas exchange and lung recruitability [PDF]

Annals of Intensive Care, 2021
Background The ARDS is characterized by different degrees of impairment in oxygenation and distribution of the lung disease. Two radiological patterns have been described: a focal and a diffuse one.
Silvia Coppola, Tommaso Pozzi, Martina Gurgitano, Alessandro Liguori, Ejona Duka, Francesca Bichi, Arianna Ciabattoni, Davide Chiumello   +7 more
doaj   +3 more sources

Induction of severe hypoxemia and low lung recruitability for the evaluation of therapeutic ventilation strategies: a translational model of combined surfactant-depletion and ventilator-induced lung injury [PDF]

Intensive Care Medicine Experimental, 2022
Background Models of hypoxemic lung injury caused by lavage-induced pulmonary surfactant depletion are prone to prompt recovery of blood oxygenation following recruitment maneuvers and have limited translational validity. We hypothesized that addition of
Emilia Boerger, Martin Russ, Philip von Platen, Mahdi Taher, Lea Hinken, Anake Pomprapa, Rainer Koebrich, Frank Konietschke, Jan Adriaan Graw, Burkhard Lachmann, Wolfgang Braun, Steffen Leonhardt, Philipp A. Pickerodt, Roland C. E. Francis   +13 more
doaj   +3 more sources

Monitoring lung recruitability during recruitment maneuvers in children with respiratory failure on ECMO using electrical impedance tomography: case report [PDF]

Frontiers in Pediatrics
IntroductionCurrently, there are no clear guidelines regarding the use of recruitment maneuvers in pediatric patients with severe respiratory failure who are on extracorporeal membrane oxygenation (ECMO), nor is there consensus on how they should be ...
Jan-Christoph Clausen, Jan-Christoph Clausen, Annemarie Krauß, Annemarie Krauß, Antonia Schulz, Antonia Schulz, Antonia Schulz, Antonia Schulz, Oliver Miera, Oliver Miera   +9 more
doaj   +4 more sources

Regional Lung Recruitability During Pneumoperitoneum Depends on Chest Wall Elastance – A Mechanical and Computed Tomography Analysis in Rats [PDF]

Frontiers in Physiology, 2018
Background: Laparoscopic surgery with pneumoperitoneum increases respiratory system elastance due to the augmented intra-abdominal pressure. We aim to evaluate to which extent positive end-expiratory pressure (PEEP) is able to counteract abdominal ...
Lucia Comuzzi, Lucia Comuzzi, Mariana B. de Abreu, Gabriel C. Motta-Ribeiro, Renata T. Okuro, Thiago Barboza, Niedja Carvalho, Umberto Lucangelo, Alysson R. Carvalho, Alysson R. Carvalho, Walter A. Zin   +10 more
doaj   +4 more sources

Physiology-guided personalized mechanical ventilation to prevent ventilator-induced lung injury [PDF]

Frontiers in Medicine
Mechanical ventilation is essential for managing acute respiratory failure, yet it carries a significant risk of ventilator-induced lung injury (VILI). Lung-protective ventilation, most notably through the use of low tidal volumes, has improved outcomes ...
Raffaele Merola, Denise Battaglini, Denise Battaglini, Marcus J. Schultz, Marcus J. Schultz, Marcus J. Schultz, Marcus J. Schultz, Patricia R. M. Rocco   +7 more
doaj   +2 more sources

Impact of PEEP on V/Q mismatch according to patient position and recruitability: a clinical prospective study [PDF]

Annals of Intensive Care
Background: High positive end-expiratory pressure (PEEP) may improve ventilation-perfusion (V/Q) mismatch in acute respiratory distress syndrome (ARDS) patients with high recruitability in supine position.
Zhiqian Zha, Zhichang Wang, Qiyu Cheng, Shanshan Meng, Jingyuan Xu, Jianfeng Xie, Haibo Qiu, Yi Yang, Fengmei Guo   +8 more
doaj   +2 more sources

Characterizing heterogeneity and subphenotyping acute respiratory distress syndrome with computed tomography [PDF]

Intensive Care Medicine Experimental
Acute respiratory distress syndrome (ARDS) is a heterogeneous clinical syndrome rather than a single disease. Patients who meet the same diagnostic criteria may differ in lung morphology, mechanical properties, biological injury, and clinical course ...
Roberta Garberi, Matthieu Jabaudon, Sam Bayat, Sarah E. Gerard, Aurora Magliocca, Mariangela Pellegrini, Alberto Bravin, Lorraine B. Ware, John J. Marini, Yi Xin, John G. Laffey, Maurizio Cereda, Emanuele Rezoagli   +12 more
doaj   +2 more sources

EIT-based ventilation phenotypes of left-to-right asymmetry and ventral-to-dorsal center in PEEP titration in ARDS [PDF]

Respiratory Research
Background Ventilation distribution assessed by electrical impedance tomography (EIT) has great interests in acute respiratory distress syndrome (ARDS).
Xiaotong Sun, Yi Chi, Siyi Yuan, Zhanqi Zhao, Jing Jiang, Yutong Zhao, Yelin Gao, Jin Yang, Yunxing Cao, Mengru Xu, Qianlin Wang, Jingbing Han, Yun Long, Huaiwu He   +13 more
doaj   +2 more sources

Lung Recruitability of COVID-19 Pneumonia in Patients Undergoing Helmet CPAP [PDF]

Archivos De Bronconeumologia, 2021
Stefano Aliberti, Francesco Blasi, Edoardo Simonetta   +2 more
exaly   +2 more sources