Open lung ventilation with low tidal volumes, staircase recruitment maneuvers, high PEEP and decremental PEEP titration vs ARDSNet in ARDS: A systematic review and meta-analysis. [PDF]
Zeng S +7 more
europepmc +1 more source
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang +11 more
wiley +1 more source
Artificial intelligence in ARDS: From automated support to personalized ventilation. [PDF]
Muñoz J +3 more
europepmc +1 more source
USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui +5 more
wiley +1 more source
Computed tomography in ARDS, from morphological insights to AI-powered multi-modal analysis: a narrative review. [PDF]
Xu Z +5 more
europepmc +1 more source
Imaging and pulmonary function techniques in ARDS diagnosis and management: current insights and challenges. [PDF]
Battaglini D +4 more
europepmc +1 more source
Personalized positive-end expiratory pressure using electrical impedance tomography in ARDS patients: a systematic review and meta-analysis. [PDF]
Rauseo M +11 more
europepmc +1 more source
Electrical impedance tomography-guided individualized ventilation strategy in patients with trauma-related and postoperative acute respiratory distress syndrome. [PDF]
Nguyen Viet M +4 more
europepmc +1 more source
PURPOSE: To clarify whether the gas exchange response to prone position is associated with lung recruitability in mechanically ventilated patients with acute respiratory failure.
Massimo Cressoni, Alessandro Protti
exaly +2 more sources
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