Results 51 to 60 of about 1,490,261 (247)

The assessment of regional lung mechanics with electrical impedance tomography: a pilot study during recruitment manouvres

, 2008
The purpose of lung recruitment manoeuvres is to open collapsed lung regions, improve gas exchange and optimise regional lung mechanics. This study investigates the efficacy of recruitment manoeuvres for improving regional ventilation distribution as ...
Dunster, Kimble R., Schibler, Andreas, Grant, Caroline A., Fraser, John F.   +3 more
core   +1 more source

Utility of bedside lung ultrasound for assessment of lung recruitment in a case of acute respiratory distress syndrome

Lung India, 2019
Lung recruitment maneuvers are rescue measures commonly used to improve oxygenation in severely hypoxemic patients with acute respiratory distress syndrome (ARDS), who fail to improve on standard treatment.
Abhijeet Singh, Ayush Gupta, Manas Kamal Sen, Jagdish Chander Suri, Shibdas Chakrabarti, Dipak Bhattacharya   +5 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Tacrolimus and cyclosporine have differential effects on the risk of development of bronchiolitis obliterans syndrome: results of a prospective, randomized international trial in lung transplantation.

, 2012
Chronic lung allograft dysfunction, which manifests as bronchiolitis obliterans syndrome (BOS), is recognized as the primary cause of morbidity and mortality after lung transplantation.
Klepetko, Walter, European and Australian Investigators in Lung Transplantation, Glanville, A.R., Aubert, John-David, Knoop, C., Vettorazzi, Eik, Aubert, J.D., Aboyoun, Christina, Klepetko, W., Vettorazzi, E., Reichenspurner, H., Reichenspurner, Hermann, Treede, Hendrik, Glanville, Allan R., Knoop, Christiane, Bravo, Carlos, Lama, Raffael, Lama, R., European,, Aboyoun, C., Bravo, C., Treede, H.   +21 more
core   +1 more source

Ultrasonography in the Assessment of Lung Recruitment in Patients with Severe Pneumonia

Неотложная медицинская помощь, 2020
BACKGROUND. Ultrasound study significantly expanded the possibilities of bedside diagnosis in patients with respiratory failure. Using ultrasound, it is possible to determine the volume of lung damage in the form of collapsed alveoli and infiltration ...
R. Y. Lakhin, E. A. Zhirnova, V. V. Shustrov, S. G. Shulman, A. A. Yemelyanov, B. N. Bogomolov   +5 more
doaj   +1 more source

Effects of positive end-expiratory pressure and recruitment maneuvers in a ventilator-induced injury mouse model. [PDF]

PLoS ONE, 2017
Positive-pressure mechanical ventilation is an essential therapeutic intervention, yet it causes the clinical syndrome known as ventilator-induced lung injury.
Laura A Cagle, Lisa M Franzi, Angela L Linderholm, Jerold A Last, Jason Y Adams, Richart W Harper, Nicholas J Kenyon   +6 more
doaj   +1 more source

Platelet-Mediated NET Release Amplifies Coagulopathy and Drives Lung Pathology During Severe Influenza Infection

Frontiers in Immunology, 2021
The influenza A virus (IAV) causes a respiratory tract infection with approximately 10% of the population infected by the virus each year. Severe IAV infection is characterized by excessive inflammation and tissue pathology in the lungs.
Seok-Joo Kim, Agostina Carestia, Braedon McDonald, Amanda Z. Zucoloto, Heidi Grosjean, Rachelle P. Davis, Madison Turk, Victor Naumenko, Silvio Antoniak, Nigel Mackman, Mohamed Sarjoon Abdul-Cader, Mohamed Faizal Abdul-Careem, Morley D. Hollenberg, Craig N. Jenne   +13 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Monitoring lung recruitability during recruitment maneuvers in children with respiratory failure on ECMO using electrical impedance tomography: case report

Frontiers in Pediatrics
IntroductionCurrently, there are no clear guidelines regarding the use of recruitment maneuvers in pediatric patients with severe respiratory failure who are on extracorporeal membrane oxygenation (ECMO), nor is there consensus on how they should be ...
Jan-Christoph Clausen, Jan-Christoph Clausen, Annemarie Krauß, Annemarie Krauß, Antonia Schulz, Antonia Schulz, Antonia Schulz, Antonia Schulz, Oliver Miera, Oliver Miera   +9 more
doaj   +1 more source

Dynamic lung aeration and strain with positive end-expiratory pressure individualized to maximal compliance versus ARDSNet low-stretch strategy: a study in a surfactant depletion model of lung injury

Critical Care, 2023
Background Positive end-expiratory pressure (PEEP) individualized to a maximal respiratory system compliance directly implies minimal driving pressures with potential outcome benefits, yet, raises concerns on static and dynamic overinflation, strain and ...
Congli Zeng, Min Zhu, Gabriel Motta-Ribeiro, David Lagier, Takuga Hinoshita, Mingyang Zang, Kira Grogg, Tilo Winkler, Marcos F. Vidal Melo   +8 more
doaj   +1 more source