Results 121 to 130 of about 164,398 (291)

Pretransplant gastroesophageal reflux compromises early outcomes after lung transplantation [PDF]

open access: yes, 2011
ObjectivesGastroesophageal reflux disease (GERD) is implicated as a risk factor for bronchiolitis obliterans syndrome after lung transplantation, but its effects on acute rejection, early allograft function, and survival are unclear. Therefore, we sought
Blackstone, Eugene H.   +9 more
core   +1 more source

Lung and heart-lung transplantation

open access: yesCardiology in the Young, 2009
I NCREASED UNDERSTANDING AND AWARENESS OF congenital cardiac disease has allowed early identification of these children. Advances in surgical techniques, anesthesia, and medical treatment have rendered the majority of forms of congenital cardiac defects treatable.
Date, Hiroshi, Sweet, Stuart C
openaire   +5 more sources

Inhalable Hsa‐miR‐30a‐3p Liposomes Attenuate Pulmonary Fibrosis

open access: yesAdvanced Science, EarlyView.
The study explores inhalable hsa‐miR‐30a‐3p‐loaded liposomes as a treatment for bleomycin‐induced pulmonary fibrosis in mice. Hsa‐miR‐30a‐3p is electroporated into liposomes and formulated into a dry powder for inhalation. Delivered via dry powder inhalation, it improves pulmonary function, promotes myofibroblast de‐differentiation by targeting CNPY2 ...
Shuo Liu   +14 more
wiley   +1 more source

Minimally invasive double lung transplantation technique (Anteroaxillary approach) [PDF]

open access: yes, 2012
Lung transplantation has been performed through several approaches in the past. Sternothoracotomy is the most widely used approach for double lung transplantation.
Sareyyupoglu, B, Toyoda, Y, Yucel, O
core   +2 more sources

Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles

open access: yesAdvanced Science, EarlyView.
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon   +25 more
wiley   +1 more source

Treprostinil inhibits proliferation and extracellular matrix deposition by fibroblasts through cAMP activation

open access: yesScientific Reports, 2018
Idiopathic pulmonary fibrosis (IPF) is characterized by peripheral lung fibrosis and increased interstitial extracellular matrix (ECM) deposition. In IPF, tumor growth factor (TGF)-β1 which is the major stimulus of ECM deposition, and platelet derived ...
Christopher Lambers   +7 more
doaj   +1 more source

Cost-effectiveness of lung transplantation in The Netherlands: a scenario analysis [PDF]

open access: yes, 1998
STUDY OBJECTIVES: To calculate cost-effectiveness of scenarios concerning lung transplantation in The Netherlands. DESIGN: Microsimulation model predicting survival, quality of life, and costs with and without transplantation program, based on data of
Al, M.J. (Maiwenn)   +6 more
core  

Challenges in lung transplantation

open access: yesSwiss Medical Weekly, 2011
Lung transplantation is an established therapy for end-stage pulmonary disorders in selected patients without significant comorbidities. The particular constraints associated with organ transplantation from deceased donors involve specific allocation rules in order to optimise the medical efficacy of the procedure.
Thorsten Krueger   +2 more
openaire   +4 more sources

Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study reveals that KMT5C activates DNA damage repair to inhibit STING‐IRF3 pathway, downstream type I IFN signaling and CCL5 secretion, leading to the downregulation of CD8+ T cell infiltration and function in NSCLC, ultimately facilitating tumor progression.
Yunfeng Yuan   +11 more
wiley   +1 more source

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