Results 191 to 200 of about 214,416 (313)

One and One-Half Year Experience with Unilateral and Bilateral Lung Transplantation

open access: gold, 1992
Walter Klepetko   +8 more
openalex   +1 more source

Activation of USP30 Disrupts Endothelial Cell Function and Aggravates Acute Lung Injury Through Regulating the S‐Adenosylmethionine Cycle

open access: yesAdvanced Science, EarlyView.
USP30 deubiquitinates and stabilizes MAT2A, thereby regulating DNA methylation and miRNA expression, which ultimately leads to disruption of lung endothelial barrier and inflammation. Abstract Microvascular dysfunction is a key contributor to the development of acute inflammatory diseases, characterized by heightened vascular hyperpermeability and ...
Baoyinna Baoyinna   +11 more
wiley   +1 more source

CD38-targeted therapy with Daratumumab in clinical lung transplantation: A single-center experience. [PDF]

open access: yesJHLT Open
Hillebrand C   +14 more
europepmc   +1 more source

In-storage Hypothermic Perfusion for Heart and Lung Transplantation

open access: bronze, 1992
Masaya Kitamura   +9 more
openalex   +1 more source

Overcoming EGFR‐Mediated Dendritic Cell Dysfunction to Enhance Anti‐tumor Immunity in EGFR‐Mutant NSCLC by Precisely Targeting CD73 With pH‐responsive Nanocarriers

open access: yesAdvanced Science, EarlyView.
EGFR mutations drive ERK/c‐Jun–mediated transcriptional activation of CD73, elevating adenosine levels and fostering an immunosuppressive TME by impairing DC maturation and CD8⁺ T cell priming. The pH‐responsive nanodrug F127ZIF‐8AB680 selectively inhibits CD73, normalizes adenosine metabolism, and re‐establishes effective anti‐tumor immunity ...
Xiaoling Shang   +14 more
wiley   +1 more source

Pulmonary endarterectomy for chronic thromboembolic pulmonary hypertension after bilateral lung transplantation. [PDF]

open access: yesJHLT Open
Battilana B   +7 more
europepmc   +1 more source

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang   +18 more
wiley   +1 more source

Primary Graft Dysfunction in Lung Transplantation: An Overview of the Molecular Mechanisms. [PDF]

open access: yesInt J Mol Sci
Jennekens J   +6 more
europepmc   +1 more source

Pediatric lung transplantation

open access: bronze, 1994
Thomas L. Spray   +3 more
openalex   +1 more source

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