Results 191 to 200 of about 355,907 (356)

A Human Immuno‐Lung Organoid Model to Study Macrophage‐Mediated Lung Cell Senescence Upon SARS‐CoV‐2 Infection

Advanced Science, EarlyView.
Immuno‐lung organoids are developed and used spatial transcriptomics to uncover how proinflammatory macrophages drive lung cell senescence via the THBS1–(ITGA3+ITGB1) axis in COVID‐19. To ensure broad accessibility, LungSpatialDB is created, an AI‐powered data portal, enabling intuitive exploration of spatial data and biological insights through ...
Yuling Han, Dongliang Leng, Tuo Zhang, Jian Ge, Yinshan Fang, Tiankun Lu, Xue Dong, Manoj S Nair, Neranjan de Silva, Zhaowei Han, Tiancheng Jiao, Yuanhao Huang, Meiqi Zhao, Anjali Saqi, Hanina Hibshoosh, Zihe Meng, Jenny Z Xiang, Chendong Pan, Yanjie Sun, David D. Ho, Todd Evans, Jie Liu, Liuliu Yang, Jianwen Que, Shuibing Chen   +24 more
wiley   +1 more source

Indications for pediatric lung transplantation in 2025: A new era. [PDF]

JHLT Open
Avdimiretz N, Hayes D, Solomon M, Schwerk N, Benden C.   +4 more
europepmc   +1 more source

Pulmonary infiltrates after heart-lung transplantation: Evaluation by serial transbronchial biopsies

, 1989
Vaughn A. Starnes, Philip E. Oyer, Edward B. Stinson, Carlos E. Moreno-Cabral, Richard Sibley, Norman E. Shumway, James Theodore, Gerald Barry   +7 more
openalex   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y.S. Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang   +14 more
wiley   +1 more source

Exogenous surfactant therapy in thirty-eight hour lung graft preservation for transplantation [PDF]

, 1994
Richard J. Novick, Ruud A. W. Veldhuizen, Fred Possmayer, J. Jack Lee, David Sandler, James F. Lewis   +5 more
openalex   +1 more source

Macrophage Derived Galectin‐3 Promotes Renal Fibrosis and Diabetic Kidney Disease by Enhancing TGFβ1 Signaling

Advanced Science, EarlyView.
Macrophage‐derived Galectin‐3 amplifies TGFβ1 signaling to drive diabetic kidney fibrosis: a novel therapeutic target. Abstract Over 30% of patients with type 2 diabetes develop diabetic kidney disease (DKD), which has emerged as a major contributor to end stage renal disease.
Yibing Chen, Qian Jiang, Xiaowei Xing, Liu Xu, Qijin Zhao, Qidong Zhang, Jingwen Chen, Chunxiao Ma, Xingfeng Liu, Yinfei Lu, Yanjun Wan, Lijuan Kong, Shaocong Hou, Qian Lu, Bing Cui, Jiankan Guo, Hongdong Huang, Pingping Li   +17 more
wiley   +1 more source

Cryoanalgesia in Lung Transplantation - A Systematic Review and Meta-analysis. [PDF]

JHLT Open
Passos FS, Bregion PB, Oliveira RE, Siemeni T, Treml RE, Pessoa BM, Kirov H, Doenst T, Keshavjee S, Caldonazo T.   +9 more
europepmc   +1 more source

Combined heart-lung transplantation for end-stage Eisenmenger’s syndrome

, 1986
Christopher G.A. McGregor, S. W. Jamieson, John C. Baldwin, C Burke, K Dawkins, Edward B. Stinson, P E Oyer, Margaret E. Billingham, Douglas R. Zusman, B. A. Reitz, Andrew Morris, Samuel A. Yousem, Sharon A. Hunt, Norman E. Shumway   +13 more
openalex   +1 more source

BCG‐Derived Outer Membrane Vesicles Induce TLR2‐Dependent Trained Immunity to Protect Against Polymicrobial Sepsis

Advanced Science, EarlyView.
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong, Wenyan Hao, Lingqi Xu, Yingyi Yang, Zhenzhen Dong, Peng Pan, Zhenjiang Bai, Jie Huang, Kaidi Yang, Zhu Jin, Rui Kang, Qiang Shan, Jiang huai Wang, Zijian Zhou, Daolin Tang, Jian Wang, Huiting Zhou   +16 more
wiley   +1 more source

Lung transplantation in a patient with severe bronchiolitis obliterans secondary to Castleman disease. [PDF]

Respir Med Case Rep
Hommelgaard L, Perch M, Bendstrup E.
europepmc   +1 more source