Results 201 to 210 of about 374,691 (355)

Positive Feedback Loop of Histone Lactylation‐Driven HNRNPC Promotes Autophagy to Confer Pancreatic Ductal Adenocarcinoma Gemcitabine Resistance

open access: yesAdvanced Science, EarlyView.
Histone 3 lysine18 lactylation (H3K18la) drives heterogeneous nuclear ribonucleoprotein C (HNRNPC) overexpression, activating autophagy to mediate gemcitabine resistance by stabilizing TNF receptor‐associated factor 6 (TRAF6) mRNA. Concurrently, HNRNPC stabilizes aldehyde dehydrogenase 1 family member A3 (ALDH1A3) mRNA, which enhances glycolysis and ...
Xi‐Tai Huang   +9 more
wiley   +1 more source

Normothermic regional perfusion for donation after circulatory death in lung transplantation. [PDF]

open access: yesFront Cardiovasc Med
Gorton AJ   +3 more
europepmc   +1 more source

Spontaneous pneumothorax in a single lung transplant recipient-a blessing in disguise: A case report

open access: diamond, 2020
Himanshu Deshwal   +5 more
openalex   +1 more source

Targeting the SOX9/TIMP1 Axis with iRGD‐Conjugated Nanoplatform Enhances Dendritic Cell Function and Photodynamic Immunotherapy in Gastric Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies the SOX9/TIMP1 axis as a key regulator of immune evasion in gastric cancer. iRGD‐conjugated nanoparticles co‐delivering si‐SOX9, Ce6, and L‐Arg are developed to synergize with photodynamic therapy. The nanoplatform suppresses tumor growth, promotes dendritic cell maturation, and enhances CD8+ T‐cell activation, offering a ...
Banghua Zhong   +3 more
wiley   +1 more source

Redo Lung Transplantation After Heart-lung Transplantation. [PDF]

open access: yesAnn Thorac Surg Short Rep
Chan JCY, Geraci TC, Angel LF, Chang SH.
europepmc   +1 more source

EM2, a Natural Product MST1/2 Kinase Activator, Suppresses Non‐Small Cell Lung Cancer via Hippo Pathway Activation

open access: yesAdvanced Science, EarlyView.
EM2 directly binds to and activates MST1/2, enhancing their kinase activity and sequentially promoting LATS phosphorylation, which increases YAP phosphorylation. Consequently, YAP nuclear translocation is suppressed, leading to reduced transcription of downstream targets CTGF and CYR61, ultimately exerting a robust inhibitory effect on NSCLC cell ...
Siyu Yang   +15 more
wiley   +1 more source

Anesthesia for lung transplantation: A narrative review. [PDF]

open access: yesJ Anaesthesiol Clin Pharmacol
Khanna S, Das J, Kumar S, Mehta Y.
europepmc   +1 more source

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