Results 101 to 110 of about 815,365 (380)

Extraction of reliable information from time-domain pressure and flow signals measured by means of forced oscillation techniques [PDF]

, 2014
This paper aims to give a proof-of-concept for the possible application of the forced oscillation lung function test to assess the viscoelastic properties of the airways and tissue.
Baleanu, Dumitru, Ionescu, Clara-Mihaela, Nigmatullin, Raoul R, Osokin, Serghei I   +3 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Flow-controlled ventilation (FCV) improves regional ventilation in obese patients – a randomized controlled crossover trial

BMC Anesthesiology, 2020
Background In obese patients, high closing capacity and low functional residual capacity increase the risk for expiratory alveolar collapse. Constant expiratory flow, as provided by the new flow-controlled ventilation (FCV) mode, was shown to improve ...
Jonas Weber, Leonie Straka, Silke Borgmann, Johannes Schmidt, Steffen Wirth, Stefan Schumann   +5 more
doaj   +1 more source

Effect of forced deflation maneuvers upon measurements of respiratory mechanics in ventilated infants [PDF]

, 2018
Objective: To determine the effect of forced deflation maneuvers on respiratory mechanics and to assess the reproducibility of such measurements in intubated infants with lung disease. Design and setting: Prospective study in the pediatric intensive care
Hammer, Jürg, Newth, Christopher, Patel, Neal   +2 more
core  

A medical information system for monitoring respiratory function and related nonlinear dynamics [PDF]

, 2019
In this paper the nonlinear effects in the respiratory systems at low frequencies are measured and evaluated in healthy children and healthy adults. To this aim forced oscillations technique (FOT) has been used to non-invasively measure the lung tissue ...
Copot, Dana, Ghita, Maria, Ghita, Mihaela, Ionescu, Clara-Mihaela   +3 more
core   +1 more source

Lung Volume Measurement with the Hisense CASApplication in Preoperative Evaluation of Pediatric Pectus Excavatum [PDF]

, 2023
Jianing Shi, Qian Dong, Feifei Wang, Xianjun Zhou, Fujiang Li, Yao Liu, Ying He, Maoqing Xing   +7 more
openalex   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Standardisation of the measurement of lung volumes [PDF]

European Respiratory Journal, 2005
Wanger J, Clausen JL, Coates A, Pedersen OF, BRUSASCO, VITO, Burgos F, Casaburi R, Crapo R, Enright P, van der Grinten CP, Gustafsson P, Hankinson J, Jensen R, Johnson D, Macintyre N, McKay R, Miller MR, Navajas D, Pellegrino R, Viegi G.   +19 more
openaire   +5 more sources

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Polydatin ameliorates ovalbumin‐induced asthma in a rat model through NCOA4‐mediated ferroautophagy and ferroptosis pathway

FEBS Open Bio, EarlyView.
In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li, Yuwei Tang, Wenkang Liu, Fang Fang, Jiepeng Wang, Chaoyi Fang   +5 more
wiley   +1 more source