Results 41 to 50 of about 254,391 (317)

The application of multiple metrics in deformable image registration for target volume delineation of breast tumor bed

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Background and purpose For postoperative breast cancer patients, deformable image registration (DIR) is challenged due to the large deformations and non‐correspondence caused by tumor resection and clip insertion. To deal with it, three metrics (fiducial‐, region‐, and intensity‐based) were jointly used in DIR algorithm for improved accuracy ...
Xin Xie   +6 more
wiley   +1 more source

Quantifying lung aeration in neonatal lambs at birth using lung ultrasound

open access: yesFrontiers in Pediatrics, 2022
BackgroundLung ultrasound (LUS) is a safe and non-invasive tool that can potentially assess regional lung aeration in newborn infants and reduce the need for X-ray imaging.
Emily J. Pryor   +20 more
doaj   +1 more source

Entropy Production and the Pressure-Volume Curve of the Lung [PDF]

open access: yes, 2015
We investigate analytically the production of entropy during a breathing cycle in healthy and diseased lungs. First, we calculate entropy production in healthy lungs by applying the laws of thermodynamics to the well-known transpulmonary pressure-volume ($P-V$) curves of the lung under the assumption that lung tissue behaves as an entropy spring-like ...
arxiv   +1 more source

Influence of lung physical properties on its flow--volume curves using a detailed multi-scale mathematical model of the lung [PDF]

open access: yesarXiv, 2022
We develop a mathematical model of the lung that can estimate independently the air flows and pressures in the upper bronchi. It accounts for the lung multi-scale properties and for the air-tissue interactions. The model equations are solved using the Discrete Fourier Transform, which allows quasi instantaneous solving, in the limit of the model ...
arxiv  

Ablation of LRP6 in alpha‐smooth muscle actin‐expressing cells abrogates lung inflammation and fibrosis upon bleomycin‐induced lung injury

open access: yesFEBS Letters, EarlyView.
Low‐density lipoprotein receptor‐related protein 6 (LRP6) is a key receptor for the Wnt antagonist Dickkopf1 (DKK1). DKK1 protein expression is induced in a bleomycin (BLM)‐induced lung injury model. We show that DKK1 induces proinflammatory and profibrotic genes in lung fibroblasts.
Eun‐Ah Sung   +6 more
wiley   +1 more source

Evaluation of intrafraction couch shifts for proton treatment delivery in head‐and‐neck cancer patients: Toward optimal imaging frequency

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Purpose Treatment planning for head‐and‐neck (H&N) cancer, in particular oropharynx, nasopharynx, and paranasal sinus cases, at our center requires noncoplanar proton beams due to the complexity of the anatomy and target location. Targeting accuracy for all beams is carefully evaluated by using image guidance before delivering proton beam ...
Nrusingh C. Biswal   +5 more
wiley   +1 more source

Defining of the Relationship Between Lung Volumes, Airway Resistance and the Apnea-Hypopnea Index

open access: yesTürk Uyku Tıbbı Dergisi, 2018
Objective: Obstructive Sleep Apnea syndrome (OSAS) is characterized by recurrent complete or partial narrowing of the upper respiratory tract during sleep and frequently a decrease in blood oxygen saturation. Upper respiratory tract gap is determined by
Gülgün Çetintaş Afşar   +3 more
doaj   +1 more source

Optoelectronic Plethysmography has Improved our Knowledge of Respiratory Physiology and Pathophysiology

open access: yesSensors, 2008
It is well known that the methods actually used to track thoraco-abdominal volume displacement have several limitations. This review evaluates the clinical usefulness of measuring chest wall kinematics by optoelectronic plethysmography [OEP].
Barbara Lanini   +7 more
doaj   +1 more source

Lung volume measurements [PDF]

open access: yesEuropean Respiratory Journal, 2008
To the Editor: I read with interest the impressive paper by Cazzola et al. 1 in a recent issue of the European Respiratory Journal . However, I felt somewhat uneasy reading the recommendations on lung volume measurements, i.e. closing circuit dilution …
openaire   +2 more sources

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

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