Results 71 to 80 of about 254,391 (317)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Detecting Lung Cancer Trends by Leveraging Real-World and Internet-Based Data: Infodemiology Study

Journal of Medical Internet Research, 2020
BackgroundInternet search data on health-related terms can reflect people’s concerns about their health status in near real time, and hence serve as a supplementary metric of disease characteristics. However, studies using internet search data to monitor
Xu, Chenjie, Yang, Hongxi, Sun, Li, Cao, Xinxi, Hou, Yabing, Cai, Qiliang, Jia, Peng, Wang, Yaogang   +7 more
doaj   +1 more source

Subclinical cardiac impairment relates to traditional pulmonary function test parameters and lung volume as derived from whole-body MRI in a population-based cohort study

Scientific Reports, 2021
To evaluate the relationship of cardiac function, including time-volume-curves, with lung volumes derived from pulmonary function tests (PFT) and MRI in subjects without cardiovascular diseases.
Ricarda von Krüchten, Roberto Lorbeer, Christopher Schuppert, Corinna Storz, Blerim Mujaj, Holger Schulz, Hans-Ulrich Kauczor, Annette Peters, Fabian Bamberg, Stefan Karrasch, Christopher L. Schlett   +10 more
doaj   +1 more source

Lung-Protective Ventilation Over 6 Years at a Large Academic Medical Center: An Evaluation of Trends, Adherence, and Perceptions of Benefit

Critical Care Explorations, 2021
Objectives:. The main objective of this study was to evaluate trends in set tidal volumes across all adult ICUs at a large academic medical center over 6 years, with a focus on adherence to lung-protective ventilation (≤ 8-cc/kg ideal body weight).
Catherine A. Gao, MD, Frederick M. Howard, MD, Jonathan M. Siner, MD, Thomas D. Candido, BA, Lauren E. Ferrante, MD, MHS   +4 more
doaj   +1 more source

Lung nodules segmentation from CT with DeepHealth toolkit [PDF]

arXiv, 2022
The accurate and consistent border segmentation plays an important role in the tumor volume estimation and its treatment in the field of Medical Image Segmentation. Globally, Lung cancer is one of the leading causes of death and the early detection of lung nodules is essential for the early cancer diagnosis and survival rate of patients.
arxiv  

Grouping Similar Seismocardiographic Signals Using Respiratory Information [PDF]

Signal Processing in Medicine and Biology (2017) 1-6, 2017
Seismocardiography (SCG) offers a potential non-invasive method for cardiac monitoring. Quantification of the effects of different physiological conditions on SCG can lead to enhanced understanding of SCG genesis, and may explain how some cardiac pathologies may affect SCG morphology.
arxiv   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Development and assessment of the performance of a shared ventilatory system that uses clinically available components to individualize tidal volumes

BMC Anesthesiology, 2023
Objectives To develop and assess a system for shared ventilation using clinically available components to individualize tidal volumes. Design Evaluation and in vitro validation study Setting Ventilator shortage during the SARS-CoV-2 pandemic ...
David M. Hannon, Tim Jones, Jack Conolly, Conor Judge, Talha Iqbal, Atif Shahzad, Michael Madden, Frank Kirrane, Peter Conneely, Brian H. Harte, Martin O’Halloran, John G. Laffey   +11 more
doaj   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

Molecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang, Ting Guo, Xiaofang Xing, Xijuan Liu, Xuejun Gan, Yingai Li, Yan Liu, Fei Shan, Zhouqiao Wu, Jiafu Ji, Ziyu Li   +10 more
wiley   +1 more source

The effect of abdominal bracing on respiration during a lifting task: a cross-sectional study

BMC Sports Science, Medicine and Rehabilitation, 2023
Background Abdominal bracing is a maneuver widely used by rehabilitation specialists and sports trainers to improve spinal stability. This study aimed to investigate how lifting tasks with and without abdominal bracing affect the respiratory function of ...
Martin Sembera, Andrew Busch, Alena Kobesova, Barbora Hanychova, Jan Sulc, Pavel Kolar   +5 more
doaj   +1 more source