Results 11 to 20 of about 162 (101)

Traditional Medicinal Uses, Phytoconstituents, Bioactivities, and Toxicities of Erythrina abyssinica Lam. ex DC. (Fabaceae): A Systematic Review. [PDF]

Evid Based Complement Alternat Med, 2021
Background. Many studies have been undertaken on the medicinal values of Erythrina abyssinica Lam. ex DC. (Fabaceae). The details, however, are highly fragmented in different journals, libraries, and other publication media. This study was therefore conducted to provide a comprehensive report on its ethnobotany, ethnomedicinal uses, phytochemicals, and
Obakiro SB, Kiprop A, Kigondu E, K'Owino I, Odero MP, Manyim S, Omara T, Namukobe J, Owor RO, Gavamukulya Y, Bunalema L.   +10 more
europepmc   +2 more sources

Intracellular and Extracellular Efficacy of Homoisoflavone Derivatives Against Mycobacterium Tuberculosis: Progress Toward Novel Antitubercular Agents. [PDF]

ChemMedChem
A series of 42 homoisoflavones were synthesized and evaluated against Mycobacterium tuberculosis (Mtb). Three derivatives showed potent inhibition of Mtb strains. Evaluation in infected macrophages revealed promising intracellular activity, where one derivative featuring a nitrofuranyl and piperidine group emerges as the most promising.
Calixto SD, Falcão JS, Antunes SS, Araujo MH, Cunha ALB, Martins DR, Nascimento SMR, Simão TLBV, Lasunskaia EB, Romeiro NC, Costa PRR, Muzitano MF, Caleffi GS.   +12 more
europepmc   +2 more sources

Southeast Asian Medicinal Plants as a Potential Source of Antituberculosis Agent. [PDF]

Evid Based Complement Alternat Med, 2017
Despite all of the control strategies, tuberculosis (TB) is still a major cause of death globally and one‐third of the world’s population is infected with TB. The drugs used for TB treatment have drawbacks of causing adverse side effects and emergence of resistance strains.
Sanusi SB, Abu Bakar MF, Mohamed M, Sabran SF, Mainasara MM.   +4 more
europepmc   +2 more sources

Flavonoids: A Review of Antibacterial Activity Against Gram-Negative Bacteria. [PDF]

Int J Microbiol
The rise in bacterial resistance to conventional antibiotics has led to the search for alternative antimicrobial agents, such as flavonoids, which are widely distributed in plants and known for their antibacterial properties. This review examines the antibacterial activity of flavonoids against Gram‐negative bacteria and identifies gaps in current ...
do Nascimento JB, da Costa JGM.
europepmc   +2 more sources

Antiplasmodial and larvicidal flavonoids from Derris trifoliate [PDF]

Bulletin of the Chemical Society of Ethiopia, 2009
From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified.
Abiy Yenesew, Hannington Twinomuhwezi, Jacques M. Kabaru, Hoseah M. Akala, Bernard T. Kiremire, Matthias Heydenreich, Martin G. Peter, Fredrick L. Eyase, Norman C. Waters, Douglas S. Walsh   +9 more
doaj   +2 more sources

Flavonoid, pterocarpans and steroid from Erythrina fusca Lour. growing in Bangladesh: isolation, and antimicrobial and free-radical scavenging activity

Journal of Medicinal Plants, 2021
Background: Erythrina fusca Lour. (fam. Fabaceae) is a flowering tree, found extensively in tropical and subtropical Asian countries, and is known for its use in traditional medicine for the treatment of various human ailments, for example, fever, liver ...
A Anjum, M. Z. Sultan, S Ferdosh, M Kaisarul Islam, M. A. Rashid, L Nahar, S. D. Sarker   +6 more
doaj   +1 more source

Inhibitory actions of lupinifolin isolated from Derris reticulata stem against carbohydrate-digesting enzymes [PDF]

Pharmacognosy Research, 2020
Background: Postprandial hyperglycemia is linked with the development of diabetic complications. Inhibition against the carbohydrate-digesting enzymes, specifically pancreatic α-amylase and intestinal α-glucosidase, delays carbohydrate digestion and subsides postprandial plasma glucose (PPG) levels.
Pawitra Pulbutr, Pichnatcha Nantana, Surabot Suksabai, Chawannuch Mudjupa, Rattazart Denchai, Sakulrat Rattanakiat, Taweesak Dhammaraj   +6 more
openaire   +1 more source

Traditional Medicinal Plants as a Source of Antituberculosis Drugs: A System Review

BioMed Research International, Volume 2021, Issue 1, 2021., 2021
Medicinal plants are the chief components in the different oriental formulations in different traditional medical systems worldwide. As a thriving source of medicine, the medicinal plants with antituberculosis (TB) properties inspire the pharmacists to develop new drugs based on their active components or semimetabolites.
Yuhui Xu, Bowen Liang, Chengcheng Kong, Zhaogang Sun, Jane Hanrahan   +4 more
wiley   +1 more source

Synergistic Effects of Lupinifolin-Based Flavonoid Combinations on Methicillin-Sensitive and Methicillin-Resistant Staphylococcus aureus

Tropical Journal of Natural Product Research
null Pawitra Pulbutr, null Pawina Khoneawklang, null Waraporn Chitsom, null Sakulrat Rattakiat, null Waraporn Saentaweesuk   +4 more
exaly   +2 more sources

Inhibitory activity of lupinifolin isolated from Derris reticulata stem against biofilm formation of Streptococcus mutans and Staphylococcus aureus

Pharmacognosy Research, 2020
Background: Biofilm formation activity of pathogenic bacteria plays an important role in the pathogenesis and progression of various diseases caused by bacterial infections. It has been reported that lupinifolin, a major phytochemical isolated from Derris reticulata stem, possesses an antibacterial activity against Streptococcus mutans and ...
Pawitra Pulbutr, Kaewkallaya Thongrak, Apichart Thitprapai, Sakulrat Rattanakiat, Chawannuch Mudjupa, Achida Jaruchotikamol   +5 more
openaire   +1 more source