Results 81 to 90 of about 162 (101)

Total Synthesis and Antibacterial Evaluation of Lupinifolin and Its Natural Analogues

open access: yesJournal of Natural Products
In this study, lupinifolin (1) and its natural analogues, mundulin (2), minimiorin (3), khonklonginol H (4), flemichin D (5), and eriosemaone A (27), were obtained by chemical synthesis for the first time. Key steps involved an electrocyclization to build the linear pyran rings and a Claisen/Cope rearrangement to install the 8-prenyl substituents.
Ling Mei, Hongbo Dong, Bin Long
exaly   +5 more sources

Lupinifolin from Albizia myriophylla wood: A study on its antibacterial mechanisms against cariogenic Streptococcus mutans

open access: yesArchives of Oral Biology, 2018
To determine the anti-Streptococcus mutans mechanisms of action of lupinifolin from Albizia myriophylla Benth. (Fabaceae) wood and provide scientific evidence to support the traditional use of the plant against dental caries.The minimum inhibitory concentration (MIC) was evaluated using the broth micro-dilution method.
Supayang Piyawan Voravuthikunchai   +2 more
exaly   +4 more sources

Synthesis of lupinifolin

open access: yesTetrahedron Letters, 1978
S R Gupta
exaly   +3 more sources

Development of Lipid-Based Nanocarriers for Increasing Gastrointestinal Absorption of Lupinifolin

Planta Medica, 2020
AbstractLupinifolin, a plant flavonoid, has been reported to possess various pharmacological effects. It most likely exerts low oral bioavailability because of poor water solubility. The objective of this study was to develop lipid nanocarriers as drug delivery systems to increase the gastrointestinal absorption of lupinifolin extracted from Albizia ...
Nuannoi Chudapongse
exaly   +3 more sources

Mechanism of Action and Biofilm Inhibitory Activity of Lupinifolin Against Multidrug-Resistant Enterococcal Clinical Isolates

Microbial Drug Resistance, 2019
The treatment of enterococcal infections is becoming more difficult because of multidrug resistance (MDR). Lupinifolin, a prenylated flavonoid isolated from Albizia myriophylla Benth., showed a potent antimicrobial activity against enterococci.
Supayang Piyawan Voravuthikunchai   +1 more
exaly   +3 more sources

Antidiarrhoeal Evaluation of Root Extract, Its Bioactive Fraction, and Lupinifolin Isolated from Eriosema chinense

Planta Medica, 2013
The roots of the plant Eriosema chinense are traditionally used by the tribal people of North East India for treatment of diarrhoea. Therefore, the present investigation was undertaken to scientifically validate the traditional claim that these roots have an antidiarrhoeal effect.
Satyendra K, Prasad   +3 more
exaly   +3 more sources

Lupinifolin from Derris reticulata possesses bactericidal activity on Staphylococcus aureus by disrupting bacterial cell membrane

Journal of Natural Medicines, 2016
In this study, lupinifolin, a prenylated flavonoid, was isolated from Derris reticulata stem, identified by NMR spectra and confirmed with mass spectrometry. Lupinifolin was freshly prepared by solubilizing in 0.1 N NaOH and immediately diluted in Müller-Hinton broth for antibacterial testing.
Oratai Weeranantanapan   +1 more
exaly   +3 more sources

Synergistic antibacterial and antibiofilm properties of lupinifolin in combination with antibiotics against pathogenic bacteria

Archives of Microbiology
Lupinifolin possesses the capability to combat specific pathogenic bacteria. Nonetheless, Gram-negative bacteria exhibit minimal inhibition by lupinifolin. This study evaluated the synergistic antibacterial and antibiofilm activities of combinations of lupinifolin and antibiotics against pathogenic bacteria using a checkerboard assay and time-kill ...
Mingkwan Yingkajorn   +1 more
exaly   +3 more sources

ChemInform Abstract: SYNTHESIS OF (.+‐.) LUPINIFOLIN, DI‐O‐METHYLXANTHOHUMOL ‐ISOXANTHOHUMOL AND RELATED COMPOUNDS

Chemischer Informationsdienst, 1979
AbstractPrenylierung von Naringenin (I) mit dem Methylbutenol (II) gibt ein Gemisch der Verbindungen (III); beim Erhitzen mit HCOOH cyclisieren die Prenylnaringenine (IIIa), (IIIb) bzw. (IIIc) zu den Pyrano‐Derivaten (IV) und (V) (VI) bzw. (VII).
A. C. JAIN, R. C. GUPTA, P. D. SARPAL
openaire   +1 more source

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