Results 171 to 180 of about 220,826 (265)

Transitioning from invasive to liquid biopsy techniques: a bibliometric analysis and prospective insights on biomarkers in lupus nephritis. [PDF]

Front Med (Lausanne)
Liu C, Chen Y, Li X, Huang S, Fan Y, Bao J.   +5 more
europepmc   +1 more source

Lupus Vulgaris [PDF]

BMJ, 1937
openaire   +2 more sources

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

Late-onset recurrent lupus nephritis in a kidney transplant recipient. [PDF]

Clin Nephrol Case Stud
Cobb JK, Endres P, Shenoy P, Filippone EJ, Gupta M, Gulati R.   +5 more
europepmc   +1 more source

Pharmacokinetics, effectiveness and safety of certolizumab pegol in children and adolescents with active juvenile idiopathic arthritis: 9+‐year results from a multicenter, open‐label study

Arthritis &Rheumatology, Accepted Article.
Objective To assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients 2–17 years with active pcJIA and inadequate response ...
Hermine I Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel Lovell, Nicolino Ruperto   +28 more
wiley   +1 more source

Upregulated GLUT1 expression correlates with type I interferon activity and disease severity in cutaneous lupus erythematosus. [PDF]

J Transl Autoimmun
Bokor LA, Szabolcs BL, Király Z, Mohos A, Szepesi Á, Varga V, Sebestyén A, Kemény LV, Holló P, Hidvégi B.   +9 more
europepmc   +1 more source

Age‐associated B cells contribute to inflammation via antibody‐independent mechanisms in Takayasu's arteritis

Arthritis &Rheumatology, Accepted Article.
Objective Although Takayasu's arteritis (TAK) is not a prototypical autoantibody‐mediated disease, accumulating evidence suggests that B cells are involved. This study aimed to investigate the pathway of B‐cell activation and its contributions to TAK pathogenesis.
Chenglong Fang, Xiaoxi Yang, Xiaochuan Sun, Shangyi Jin, Lihong Du, Jinwei Gao, Jing Li, Zhen Chen, Yuexin Chen, Mengtao Li, Xinping Tian   +10 more
wiley   +1 more source

Targeting STAT3 in systemic lupus erythematosus and lupus nephritis: mechanisms, therapeutic advances, and structure-informed perspectives. [PDF]

Front Pharmacol
Yi F, Tu X, Jin R, Zhou J, Li Y, Liao H, Xu W, Yuan Y, Wu M, Bi P, Yin J.   +10 more
europepmc   +1 more source

Type I interferon drives dysfunction of a distinct CD8+ HLA‐DRB1+ T cell subset in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by type I interferon (IFN) signaling and adaptive immune dysregulation. We previously identified hypomethylation of HLA‐DRB1 and STAT1 in SLE CD8+ T cells, enabling aberrant IFN‐driven HLA‐DRB1 expression and expansion of a distinct CD8+ T cell subset. This study characterized CD8+ HLA‐DRB1+
Huizhong Long, Elio Carmona, Mikhail G Dozmorov, Amr H Sawalha   +3 more
wiley   +1 more source

Inhibition of neutrophil infiltration and NETs formation ameliorates neuropsychiatric and renal dysfunction in MRL/lpr mice with lupus. [PDF]

PLoS One
Deng Y, Shang Y, Zhang Y, Li D, Xiong Y, Shen Y, Liu L, Ran Y, He P, Chen S, Wu L, Hu S, Liu L, Yang Z, Zha Y, Yuan J.   +15 more
europepmc   +1 more source