Results 261 to 270 of about 295,608 (311)
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Systemic lupus erythematosus and lupus nephritis
Nature Reviews Drug Discovery, 2014The late-stage pipeline for systemic lupus erythematosus (SLE) and lupus nephritis (LN) contains biologics and small-molecule drugs for a broad range of different targets. Koutsokeras and Healy discuss their likely impact on the future SLE and LN market.
Toli, Koutsokeras, Tina, Healy
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The Journal of Family Practice, 2022
THE COMPARISON A Multicolored (pink, brown, and white) indurated plaques in a butterfly distribution on the face of a 30-year-old woman with a darker skin tone. B Pink, elevated, indurated plaques with hypopigmentation in a butterfly distribution on the face of a 19-year-old woman with a lighter skin tone.
Candrice R, Heath, Richard P, Usatine
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THE COMPARISON A Multicolored (pink, brown, and white) indurated plaques in a butterfly distribution on the face of a 30-year-old woman with a darker skin tone. B Pink, elevated, indurated plaques with hypopigmentation in a butterfly distribution on the face of a 19-year-old woman with a lighter skin tone.
Candrice R, Heath, Richard P, Usatine
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WHAT IS LUPUS? WHAT IS NOT LUPUS?
Rheumatic Disease Clinics of North America, 1993Present understanding suggests that lupus reflects a spectrum of syndromes that share many clinical, inflammatory, and immunologic features. Those patients not fulfilling criteria for systemic lupus erythematosus (SLE) do not seem to evolve frequently to classic SLE, tend to have a good prognosis, and may be managed conservatively.
R S, Panush, J M, Greer, K K, Morshedian
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LUPUS AND NON‐LUPUS CUTANEOUS MANIFESTATIONS IN SYSTEMIC LUPUS ERYTHEMATOSUS
Australian and New Zealand Journal of Medicine, 1987Abstract Mucocutaneous manifestations occur frequently in systemic lupus erythematosus (SLE). Common non‐lupus dermatoses may be confused with lupus rashes, with important clinical consequences. A study of 84 consecutive patients with SLE was performed to determine the comparative frequency of lupus and non‐lupus mucocutaneous abnormalities, the ...
C, Weinstein +5 more
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Lupus pregnancies and neonatal lupus
Springer Seminars in Immunopathology, 1994In the past two decades the diagnosis of systemic lupus erythematosus (SLE) has become easier to make and more certain when made. Advances in treatment have permitted patients with SLE to live longer and healthier lives. New clinical research has also described the role that some autoantibodies associated with SLE have on fetal well-being. As a result,
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Systemic lupus erythematosus and “lupus dyslipoproteinemia”
Autoimmunity Reviews, 2008A growing body of evidences reinforces the close link between systemic lupus erythematosus (SLE) and atherosclerosis which is due to traditional and nontraditional risk factors for cardiovascular diseases. It is now recognized that SLE has a particular pattern of dyslipoproteinemia characterized by low HDL levels and increased triglycerides, which is ...
Jozélio Freire, de Carvalho +2 more
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Archives of Dermatology, 1972
Lupus erythematosus (LE) is a multisystem disease. Genetic predisposition, altered immunity, hormones, drugs, viruses, and ultraviolet light all may play a role in etiology. A wide range of cutaneous lesions occur, and variants such as subacute cutaneous LE, complement-deficient LE, and neonatal LE have recently been emphasized.
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Lupus erythematosus (LE) is a multisystem disease. Genetic predisposition, altered immunity, hormones, drugs, viruses, and ultraviolet light all may play a role in etiology. A wide range of cutaneous lesions occur, and variants such as subacute cutaneous LE, complement-deficient LE, and neonatal LE have recently been emphasized.
openaire +3 more sources
Animal Models of Lupus and Lupus Nephritis
Current Pharmaceutical Design, 2015This article reviews the commonly used murine strains for studying lupus and lupus nephritis, including strains that develop lupus spontaneously, congenic strains, induced models of lupus, as well as genetically engineered mouse models of lupus bearing transgenes or knockouts.
Yong, Du +3 more
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