Results 141 to 150 of about 9,990 (166)
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Characterization of an acquired IgG inhibitor of coagulation factor XIII in a patient with systemic lupus erythematosus

British Journal of Haematology, 1996
An acquired IgG inhibitor to factor XIII was identified in a 30‐year‐old Vietnamese woman with systemic lupus erythematosus. The IgG fraction was isolated from plasma by chromatography on an agarose gel column and by protein G adsorption. The anti‐factor XIII activity, identified within the IgG fraction, inhibited factor XIII from both normal plasma ...
Ferhaan Ahmad   +2 more
exaly   +3 more sources

The lupus coagulation inhibitor and venous thrombosis: a report of four cases

International Journal of Laboratory Hematology, 1980
H, Williams, R, Laurent, T, Gibson
exaly   +3 more sources

New method to differentiate between lupus anticoagulants, progressive coagulation inhibitors and coagulation factor deficiencies in the mixing tests

International Journal of Laboratory Hematology
AbstractIntroductionMixing tests in activated partial thromboplastin time (APTT) are used for the differentiation between lupus anticoagulants (LA), coagulation inhibitors, and factor deficient samples with APTT prolongation. However, the indexes for the differentiation have not been established.
Daiki Shimomura   +2 more
exaly   +3 more sources

Natural inhibitors of blood coagulation and fibrinolysis in patients with lupus anticoagulant

Blood Coagulation & Fibrinolysis, 1992
We studied the natural inhibitors (NI) of blood coagulation and fibrinolysis in 50 patients with lupus anticoagulant (LA), in order to identify possible alterations of these NI, that could favour thrombotic manifestations. We found no statistically significant difference in antithrombin III, protein C and alpha 2-antiplasmin between controls and ...
L C, Kordich   +4 more
openaire   +2 more sources

A Circulating Lupus-like Coagulation Inhibitor Induced by Chlorpromazine

Journal of Clinical Psychopharmacology, 1984
A variety of immune phenomena have been associated with chlorpromazine. One such factor, the lupus-like anticoagulant, while nonspecific, has been reported in 26 to 75% of chronic chlorpromazine recipients, although the exact incidence is unknown and requires further investigation.
G, Tollefson, K, Rodysill, M, Cusulos
exaly   +3 more sources

Circulating inhibitors of blood coagulation associated with procainamide‐induced lupus erythematosus

American Journal of Hematology, 1978
AbstractWe studied a patient being treated with procainamide in whom we observed a high antinuclear antibody titer and prolonged activated partial thromboplastin (PTT), prothrombin (PT), and Stypven times (ST). Serum antibody concentrations against single‐stranded DNA were elevated while those against native DNA were not elevated, suggesting the ...
S, Davis   +4 more
openaire   +2 more sources

Changes in Components of the Natural Coagulation Inhibitor System, in Patients with Antiphospholipid Antibodies and/or the Lupus Inhibitor.

Blood, 2006
Abstract The cell surface glycoproteins thrombomodulin (TM) and endothelial protein C receptor (EPCR) are major intermediaries in the down-regulation of thrombin and are noted to be shed from endothelial cells (ECs) due to the actions of proinflammatory cytokines, thrombin and other agents.
Xuam Lam   +4 more
openaire   +1 more source

Acquired Inhibitors of Coagulation in a Patient With Systemic Lupus Erythematosus and Antiphospholipid Antibodies: Response to Rituximab

Reumatología Clínica (English Edition), 2008
Hematologic signs of systemic lupus erythematosus are diverse (SLE). Although a delayed coagulation time is anti-phospholipid antibody related, thrombotic events are the usual clinical manifestation. Spontaneous appearance of circulating anticoagulant in the absence of a previous coagulation disorder is secondary to the development of antibodies to ...
Enrique, Ortiz Jiménez   +2 more
openaire   +2 more sources

[Circulating lupus coagulation inhibitor in two sisters, one with disseminated lupus erythematosus and the other with immunologic thrombocytopenic purpura].

La Revue de medecine interne, 1993
Familial cases of lupus anticoagulant were rarely described. We report the observation of two sisters with lupus anticoagulant, one with thrombocytopenic purpura and the other with systemic lupus erythematosus.
J, Constans   +6 more
openaire   +1 more source

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