Results 131 to 140 of about 154,096 (287)
Employing latent variable models to improve efficiency in composite endpoint analysis [PDF]
Composite endpoints that combine multiple outcomes on different scales are common in clinical trials, particularly in chronic conditions. In many of these cases, patients will have to cross a predefined responder threshold in each of the outcomes to be classed as a responder overall.
arxiv
Ticlopidine-induced subacute cutaneous lupus erythematosus: A case report and literature review
Many drugs have been reported to induce lupus in a minority of patients. Ticlopidine hydrochloride inhibits platelet aggregation and is widely used for the prevention of thrombosis. There have been only a few reports of ticlopidine-induced lupus.
Yi-Ching Chen, Yu-Hung Wu
doaj +1 more source
Associação entre lúpus eritematoso e tabagismo Association between lupus erythematosus and smoking
FUNDAMENTOS: O lúpus eritematoso é doença crônica, auto-imune, que reúne manifestações exclusivamente cutâneas ou multissistêmicas, caracterizada pela produção de auto-anticorpos contra vários constituintes celulares.
Júnia Maria Fernandes Araújo+4 more
doaj +1 more source
Clonal hematopoiesis of indeterminate potential and the risk of autoimmune diseases
Abstract Background Clonal hematopoiesis of indeterminate potential (CHIP), characterized by the age‐related expansion of blood cells carrying preleukemic mutations, is associated with immune aging. This study aimed to investigate the association between CHIP and established autoimmune diseases. Methods We analyzed baseline data from 456,692 UK Biobank
Hanzhang Wu+4 more
wiley +1 more source
Introduction. Cutaneous Lupus Disease Area and Severity Index (CLASI) and its modified version, the Revised Cutaneous Lupus Erythematosus Disease Areas and Severity Index (R-CLASI) are tools for quantifying skin and mucosal lesions in patients with both ...
А. А. Shumilova+4 more
doaj +1 more source
Increasing Prevalence of Syphilis: Oral Manifestations, Diagnosis and Management
ABSTRACT Introduction Cases of syphilis are increasing, with 9513 cases diagnosed in England in 2023, the highest annual number since 1948. Oral healthcare professionals should therefore be aware of how oral syphilis presents, the differential diagnosis and the appropriate care pathway and management.
C. C. Currie+8 more
wiley +1 more source
Wasin Saowaluksakul,1 Chutima Seree-aphinan,1 Suthinee Rutnin,1 Kochawan Boonyawat,2 Kumutnart Chanprapaph1 1Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand; 2Division of ...
Saowaluksakul W+4 more
doaj
Subacute cutaneous lupus erythematosus presenting as erythroderma
Subacute cutaneous lupus erythematosus (SCLE) is a type of lupus erythematosus having distinct characteristic clinical, serologic, and genetic features. Other than the commonly occurring papulosquamous and annular polycyclic lesion, rarely it may present
Varadraj V Pai+5 more
doaj +1 more source