Results 141 to 150 of about 155,199 (206)

New insights into the progression from cutaneous lupus to systemic lupus erythematosus

Expert Review of Clinical Immunology, 2020
Introduction Between 5 and 25% of patients with cutaneous lupus erythematosus (CLE) can progress to systemic lupus erythematosus (SLE) during the course of the disease. There is no clear predictive guideline for the progression of CLE to SLE.
Wenhui Zhou, Haijing Wu, Ming Zhao, Q. Lu   +3 more
semanticscholar   +1 more source

Subacute cutaneous lupus erythematosus

Clinics in Dermatology, 1985
Abstract A large part of James N. Gilliam's abbreviated investigative career was devoted to testing a hypothesis that strong relationships do exist between the cutaneous and systemic manifestations of lupus erythematosus (LE). As a result of clinical observations made during his early studies designed to test this hypothesis, he introduced the term ...
openaire   +2 more sources

Cutaneous lupus erythematosus

Current Problems in Dermatology, 1989
Abstract Cutaneous lesions of lupus erythematosus (LE) have been classified as specific or nonspecific for LE. Common specific lesions are acute cutaneous lupus erythematosus (ACLE), subacute cutaneous lupus erythematosus (SCLE), and chronic discoid lupus erythematosus (DLE). Acute cutaneous lupus erythematosus typically consists of a transient malar
Lela A. Lee, Kathleen M. David
openaire   +1 more source

PD-1H (VISTA)–mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus

Science Translational Medicine, 2019
PD-1H (VISTA) is immunosuppressive during lupus progression and could be targeted by an agonistic antibody for therapy. Supporting a suppressor for lupus treatment Autoimmunity can result when the intricate checks and balances in the immune system are ...
Xue Han, M. Vesely, Wendy Yang, M. Sanmamed, Ti Badri, Jude Alawa, F. López-Giráldez, Patricia Gaule, S. W. Lee, Jianping Zhang, Xinxin Nie, A. Nassar, A. Boto, D. Flies, Linghua Zheng, Tae Kon Kim, G. Moeckel, J. McNiff, Lieping Chen   +18 more
semanticscholar   +1 more source

Subacute cutaneous lupus erythematosus

2000
Subacute cutaneous lupus erythematosus (SCLE) represents a relatively distinct and homogeneous subset of lupus erythematosus (LE) identified by chronic and recurrent development of characteristic erythematous, non-scarring and mostly photosensitive skin lesions associated with particular clinical, immunological and genetic features.
M. N. Manoussakis, H. M. Moutsopoulos
openaire   +1 more source

Spectrum of cutaneous lupus erythematosus in South Africans with systemic lupus erythematosus

Lupus, 2019
Background Cutaneous involvement is very common in systemic lupus erythematosus. We describe the prevalence and spectrum of lupus-specific (cutaneous lupus erythematosus) and non-specific cutaneous features amongst mostly black South Africans with ...
K. Koch, M. Tikly
semanticscholar   +1 more source

Therapy of Cutaneous Lupus Erythematosus

Medical Clinics of North America, 1982
Cutaneous lupus erythematosus occurs in a spectrum from limited cutaneous disease to severe systemic disease. Chronic DLE generally follows a benign course, but rare transformation to systemic disease may occur. Subacute cutaneous LE is associated with a specific cutaneous lesion and mild to moderate systemic symptoms.
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Disordered cutaneous microbiota in systemic lupus erythematosus.

Journal of Autoimmunity, 2019
The correlation between systemic lupus erythematosus (SLE) and microbiota colonization has been receiving much attention during recent years.
Cancan Huang, Xiaoqing Yi, H. Long, Guiying Zhang, Haijing Wu, Ming Zhao, Q. Lu   +6 more
semanticscholar   +1 more source

Investigating the presence of neutrophil extracellular traps in cutaneous lesions of different subtypes of lupus erythematosus

Experimental Dermatology, 2019
Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of systemic lupus erythematosus (SLE). However, little is known about the implication of NETs in cutaneous lupus.
R. Safi, J. Al-Hage, O. Abbas, A. Kibbi, Dany Nassar   +4 more
semanticscholar   +1 more source

Treatment of cutaneous lupus erythematosus

Lupus, 2010
In patients with cutaneous lupus erythematosus (CLE) and mild skin involvement, local therapy consisting of topically applied pharmacological agents, e.g., topical/intralesional steroids, may be sufficient. Recent reports have also shown efficacy of topical calcineurin inhibitors in patients with CLE, particularly on the face.
A, Kuhn, F, Ochsendorf, G, Bonsmann
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