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The Cutaneous Spectrum of Lupus Erythematosus
Clinical Reviews in Allergy and Immunology, 2017Systemic lupus erythematosus is a complex autoimmune disease with a wide spectrum of clinical and immunopathological features. Cutaneous and articular manifestations are the most common signs in patients with systemic lupus erythematosus. We here review the pathogenesis and the new classification of cutaneous lupus erythemathosus with a discussion of ...
Simone Ribero, Savino Sciascia
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American Journal of Clinical Dermatology, 2003
Cutaneous lupus erythematosus (CLE) includes a variety of lupus erythematosus (LE)-specific skin lesions that are subdivided into three categories - chronic CLE (CCLE), subacute CLE (SCLE) and acute CLE (ACLE) - based on clinical morphology, average duration of skin lesions and routine histopathologic examination.
FABBRI, PAOLO +3 more
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Cutaneous lupus erythematosus (CLE) includes a variety of lupus erythematosus (LE)-specific skin lesions that are subdivided into three categories - chronic CLE (CCLE), subacute CLE (SCLE) and acute CLE (ACLE) - based on clinical morphology, average duration of skin lesions and routine histopathologic examination.
FABBRI, PAOLO +3 more
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Chronic Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1989Chronic cutaneous LE is a diverse disease, characterized by predominantly cutaneous disease with few systemic complications. Discoid lesions are commonly seen, but they are not specific for chronic cutaneous LE. These scarring and disfiguring changes are also present in neonatal LE, SLE, and complement deficiency LE. Because definitive diagnosis cannot
S R, Hymes, R E, Jordon
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Treatment of cutaneous lupus erythematosus
Lupus, 2010In patients with cutaneous lupus erythematosus (CLE) and mild skin involvement, local therapy consisting of topically applied pharmacological agents, e.g., topical/intralesional steroids, may be sufficient. Recent reports have also shown efficacy of topical calcineurin inhibitors in patients with CLE, particularly on the face ...
A, Kuhn, F, Ochsendorf, G, Bonsmann
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Thalidomide in Cutaneous Lupus Erythematosus
American Journal of Clinical Dermatology, 2003For nearly 50 years, thalidomide has struggled between success and controversy. After causing an epidemic of phocomelia and other birth defects during the 1960s, affecting thousands of neonates, thalidomide was used as a sedative in selective disorders including leprosy.
Michelle T, Pelle, Victoria P, Werth
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Histopathology of cutaneous lupus erythematosus
Clinics in Dermatology, 1985The basic histopathologic feature of all cutaneous lesions of lupus erythematosus involves a perivascular mononuclear cell infiltrate with subsequent involvement of the epidermis and appendages. The various histologic alterations affecting the epidermis, dermis, and adnexal structures reflect the particular type of lesion biopsied and the duration of ...
A F, Hood, E R, Farmer
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Seminars in Cutaneous Medicine and Surgery, 2001
Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Cutaneous lupus erythematosus: a review
Dermatologic Clinics, 2002This article will review and update information about the pathogenesis, clinical presentation, diagnosis, and treatment of cutaneous lupus erythematosus. Lupus erythematosus (LE) can present as a skin eruption, with or without systemic disease. Cutaneous LE is subdivided into chronic cutaneous LE, subacute cutaneous LE and acute LE.
Purvisha, Patel, Victoria, Werth
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Therapy of Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1982Cutaneous lupus erythematosus occurs in a spectrum from limited cutaneous disease to severe systemic disease. Chronic DLE generally follows a benign course, but rare transformation to systemic disease may occur. Subacute cutaneous LE is associated with a specific cutaneous lesion and mild to moderate systemic symptoms.
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Neonatal cutaneous lupus erythematosus
Archives of Disease in Childhood - Fetal and Neonatal Edition, 2018A full-term baby girl born to a seemingly healthy mother presented at birth with an atrophic and erythematous scaly rash on her face (figure 1A) and multiple atrophic ill-defined scars distributed mainly over scalp, chest and back (figure 1B). Absence of eyebrows and eyelashes was also noted. The immune and autoimmune study was requested and both …
Henar, Romero Rey +1 more
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