Results 181 to 190 of about 29,202 (224)
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Pathogenesis of cutaneous lupus erythematosus
Clinics in Dermatology, 1985Antibody-dependent mechanisms of tissue damage are the principle mechanism of disease in systemic and cutaneous lupus erythematosus. Antibody-dependent mechanisms of keratinocyte damage appear to be a primary pathogenetic factor in all forms of papulosquamous cutaneous lupus. Photosensitive papulosquamous lupus syndromes, such as subacute cutaneous LE,
D A, Norris, L A, Lee
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The Immunopathology of Cutaneous Lupus Erythematosus
Rheumatic Disease Clinics of North America, 2014Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the development of autoantibodies and immunologic attack of different organ systems, including the skin. This review aims to provide an overview of some of the pathogenic processes that may be important in the development of SLE, specifically cutaneous lupus ...
Mark G, Kirchhof, Jan P, Dutz
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Management of cutaneous lupus erythematosus
Clinics in Dermatology, 1985Abstract Therapy of cutaneous lupus erythematosus is both an art and a science. The interplay of cosmetic and systemic factors must be understood and managed by the physician, who must, following recognition and diagnosis of the problem, discuss prognosis and life-style modification with the patient. Extensive reassurance usually is necessary.
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Subacute cutaneous lupus erythematosus
Journal of the Royal Army Medical Corps, 2016A 31-year-old female soldier developed subacute cutaneous lupus erythematosus, which remained undiagnosed for 4 years. Referral to dermatology and a punch biopsy confirmed the diagnosis and effective treatment was instituted. The presence of an unresolving annular rash in light-exposed areas, especially in a young woman, should prompt thorough ...
Jacqueline, Furzeland, P, Malcolm
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American Journal of Clinical Dermatology, 2009
Cutaneous lupus erythematosus (LE) may present in a variety of clinical forms. Three recognized subtypes of cutaneous LE are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE), and chronic cutaneous LE (CCLE). ACLE may be localized (most often as a malar or 'butterfly' rash) or generalized.
Richard D Sontheimer
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Cutaneous lupus erythematosus (LE) may present in a variety of clinical forms. Three recognized subtypes of cutaneous LE are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE), and chronic cutaneous LE (CCLE). ACLE may be localized (most often as a malar or 'butterfly' rash) or generalized.
Richard D Sontheimer
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Subacute cutaneous lupus erythematosus
Clinics in Dermatology, 1985Abstract A large part of James N. Gilliam's abbreviated investigative career was devoted to testing a hypothesis that strong relationships do exist between the cutaneous and systemic manifestations of lupus erythematosus (LE). As a result of clinical observations made during his early studies designed to test this hypothesis, he introduced the term ...
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Immunology of cutaneous lupus erythematosus
Clinics in Dermatology, 2004The cause and effect between ultraviolet light and cutaneous lupus erythematosus (CLE) is clear. In LE patients indeed, photosensitivity is one of the major diagnostic criteria of the systemic form of lupus erythematosus. This strong clinical association has led to the postulate that abnormal photosensitivity participates in the pathogenesis of ...
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Pathogenesis of cutaneous lupus erythematosus
Lupus, 2008Although for decades sunlight was suspected to be involved in the development of cutaneous lupus erythematosus (CLE), only in recent years research on the effects of ultraviolet irradiation on the skin of patients with CLE has resulted in a more comprehensive model for the pathogenesis of the disease.
Kuhn, A., Bijl, M.
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CUTANEOUS MANIFESTATIONS OF LUPUS ERYTHEMATOSUS
Rheumatic Disease Clinics of North America, 1994Lupus erythematosus is an autoimmune disease that demonstrates cutaneous, systemic, or both cutaneous and systemic manifestations. This article reviews the cutaneous manifestations of lupus erythematosus.
S D, Laman, T T, Provost
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Pathophysiology of Cutaneous Lupus Erythematosus
Clinical Reviews in Allergy & Immunology, 2007Cutaneous lupus erythematosus (LE; syn LE-specific skin disease) is an autoimmune disease with well-defined skin manifestations often accentuated in a photodistribution and frequently associated with specific autoantibodies. These clinical observations have led to numerous laboratory studies related to the role of ultraviolet light, as well as studies ...
Julie H, Lin +3 more
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