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The combined role of clinical, reflectance confocal microscopy and dermoscopy applied to chronic discoid cutaneous lupus and subacutus lupus erythematosus: A case series and literature review

Lupus, 2020
Main subtypes of cutaneous lupus erythematosus are represented by acute, subacute cutaneous, intermittent and chronic cutaneous lupus erythematosus. Discoid lupus erythematosus represents the most common phenotype of chronic cutaneous lupus erythematosus.
S. Mazzilli   +10 more
semanticscholar   +1 more source

Cutaneous Lupus Erythematosus in Children

Current Pediatric Reviews, 2021
Background:The skin is commonly involved in autoimmune diseases, such as lupus erythematous. The cutaneous lupus erythematosus (CLE) can manifest with or without systemic symptoms. It is advantageous from a patient and healthcare system standpoint for early diagnosis and intervention. Prevention of complications is especially important in the pediatric
Vivian Tsang   +2 more
openaire   +2 more sources

[Cutaneous lupus erythematosus].

Ugeskrift for laeger, 2017
Cutaneous lupus erythematosus (LE) is an autoimmune disease. The most common clinical forms are acute cutaneous LE (ACLE), subacute cutaneous LE (SCLE) and discoid LE (DLE). Cutaneous LE, mainly ACLE, can be the first sign of systemic LE (SLE). DLE and SCLE are less associated with development of SLE, however, up to 85% of patients with SLE have ...
Tatjana, Sandreva   +2 more
openaire   +3 more sources

New insights into the progression from cutaneous lupus to systemic lupus erythematosus

Expert Review of Clinical Immunology, 2020
Introduction Between 5 and 25% of patients with cutaneous lupus erythematosus (CLE) can progress to systemic lupus erythematosus (SLE) during the course of the disease. There is no clear predictive guideline for the progression of CLE to SLE.
Wenhui Zhou   +3 more
semanticscholar   +1 more source

Cutaneous lupus erythematosus.

Dermatologic therapy, 2012
Cutaneous lupus erythematosus is a heterogeneous autoimmune condition that can significantly impact quality of life. Treatment is focused on reducing clinical inflammation and preventing scarring. The choice of treatment should be guided based on the severity of disease.
Christopher B, Hansen, Kevin W, Dahle
openaire   +3 more sources

Cutaneous Lupus Erythematosus

2008
Cutaneous lupus erythematosus (CLE) is a chronic inflammatory autoimmune disorder, comprising a broad spectrum of clinical manifestations. Various environmental factors influence the clinical expression of CLE and a striking relationship has emerged between sunlight exposure and the various subtypes of this disease.
Annegret Kuhn   +2 more
openaire   +2 more sources

PD-1H (VISTA)–mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus

Science Translational Medicine, 2019
PD-1H (VISTA) is immunosuppressive during lupus progression and could be targeted by an agonistic antibody for therapy. Supporting a suppressor for lupus treatment Autoimmunity can result when the intricate checks and balances in the immune system are ...
Xue Han   +18 more
semanticscholar   +1 more source

Spectrum of cutaneous lupus erythematosus in South Africans with systemic lupus erythematosus

Lupus, 2019
Background Cutaneous involvement is very common in systemic lupus erythematosus. We describe the prevalence and spectrum of lupus-specific (cutaneous lupus erythematosus) and non-specific cutaneous features amongst mostly black South Africans with ...
K. Koch, M. Tikly
semanticscholar   +1 more source

Subacute cutaneous lupus erythematosus

Clinics in Dermatology, 1985
Abstract A large part of James N. Gilliam's abbreviated investigative career was devoted to testing a hypothesis that strong relationships do exist between the cutaneous and systemic manifestations of lupus erythematosus (LE). As a result of clinical observations made during his early studies designed to test this hypothesis, he introduced the term ...
openaire   +2 more sources

Cutaneous lupus erythematosus

Current Problems in Dermatology, 1989
Abstract Cutaneous lesions of lupus erythematosus (LE) have been classified as specific or nonspecific for LE. Common specific lesions are acute cutaneous lupus erythematosus (ACLE), subacute cutaneous lupus erythematosus (SCLE), and chronic discoid lupus erythematosus (DLE). Acute cutaneous lupus erythematosus typically consists of a transient malar
Lela A. Lee, Kathleen M. David
openaire   +1 more source

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