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Cutaneous Lupus Erythematosus in Children
Current Pediatric Reviews, 2021Background:The skin is commonly involved in autoimmune diseases, such as lupus erythematous. The cutaneous lupus erythematosus (CLE) can manifest with or without systemic symptoms. It is advantageous from a patient and healthcare system standpoint for early diagnosis and intervention. Prevention of complications is especially important in the pediatric
Vivian Tsang +2 more
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Drug-induced subacute cutaneous lupus erythematosus
Lupus, 2010 Subacute cutaneous lupus erythematosus (SCLE) is a subset of cutaneous lupus erythematosus with unique immunologic and clinical features. The first description dates back to 1985 when a series of five patients were found to have hydrochlorothiazide ...
J P Callen
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American Journal of Clinical Dermatology, 2003
Cutaneous lupus erythematosus (CLE) includes a variety of lupus erythematosus (LE)-specific skin lesions that are subdivided into three categories - chronic CLE (CCLE), subacute CLE (SCLE) and acute CLE (ACLE) - based on clinical morphology, average duration of skin lesions and routine histopathologic examination.
FABBRI, PAOLO +3 more
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Cutaneous lupus erythematosus (CLE) includes a variety of lupus erythematosus (LE)-specific skin lesions that are subdivided into three categories - chronic CLE (CCLE), subacute CLE (SCLE) and acute CLE (ACLE) - based on clinical morphology, average duration of skin lesions and routine histopathologic examination.
FABBRI, PAOLO +3 more
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Chronic Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1989Chronic cutaneous LE is a diverse disease, characterized by predominantly cutaneous disease with few systemic complications. Discoid lesions are commonly seen, but they are not specific for chronic cutaneous LE. These scarring and disfiguring changes are also present in neonatal LE, SLE, and complement deficiency LE. Because definitive diagnosis cannot
S R, Hymes, R E, Jordon
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Treatment of cutaneous lupus erythematosus
Lupus, 2010In patients with cutaneous lupus erythematosus (CLE) and mild skin involvement, local therapy consisting of topically applied pharmacological agents, e.g., topical/intralesional steroids, may be sufficient. Recent reports have also shown efficacy of topical calcineurin inhibitors in patients with CLE, particularly on the face ...
A, Kuhn, F, Ochsendorf, G, Bonsmann
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Thalidomide in Cutaneous Lupus Erythematosus
American Journal of Clinical Dermatology, 2003For nearly 50 years, thalidomide has struggled between success and controversy. After causing an epidemic of phocomelia and other birth defects during the 1960s, affecting thousands of neonates, thalidomide was used as a sedative in selective disorders including leprosy.
Michelle T, Pelle, Victoria P, Werth
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Prevalence of self-report photosensitivity in cutaneous lupus erythematosus
Journal of the American Academy of Dermatology, 2012 BackgroundLittle is known about the prevalence of self-reported photosensitivity (PS) and its effects on quality of life in a US cutaneous lupus population.ObjectiveWe sought to determine the prevalence of self-reported PS among a cutaneous lupus ...
Joyce ŌKAWA, Victoria P Werth
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Seminars in Cutaneous Medicine and Surgery, 2001
Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Lupus erythematosus (LE) has many different clinical manifestations including a variety of cutaneous findings. Some of the cutaneous manifestations are not specific for LE, such as photosensitivity reactions, oral ulcers, alopecia, urticaria, vasculitis, vesiculo-bullous lesions, acral changes, cutaneous mucinoses, and cutaneous calcinosis.
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Histopathology of cutaneous lupus erythematosus
Clinics in Dermatology, 1985The basic histopathologic feature of all cutaneous lesions of lupus erythematosus involves a perivascular mononuclear cell infiltrate with subsequent involvement of the epidermis and appendages. The various histologic alterations affecting the epidermis, dermis, and adnexal structures reflect the particular type of lesion biopsied and the duration of ...
A F, Hood, E R, Farmer
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Therapy of Cutaneous Lupus Erythematosus
Medical Clinics of North America, 1982Cutaneous lupus erythematosus occurs in a spectrum from limited cutaneous disease to severe systemic disease. Chronic DLE generally follows a benign course, but rare transformation to systemic disease may occur. Subacute cutaneous LE is associated with a specific cutaneous lesion and mild to moderate systemic symptoms.
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