Results 81 to 90 of about 154,096 (287)

Clinical factors associated with pneumocystis pneumonia despite its primary prophylaxis: When to stop prophylaxis?

Arthritis &Rheumatology, Accepted Article.
Objective Although previous studies show that primary prophylaxis against Pneumocystis jirovecii pneumonia (PJP) is effective in patients with rheumatic diseases receiving immunosuppressive treatment, there is limited evidence regarding the optimal timing for prophylaxis withdrawal.
Ju Yeon Kim, Se Rim Choi, Jin Kyun Park, Eun Young Lee, Eun Bong Lee, Jun Won Park   +5 more
wiley   +1 more source

Prevalence and clinical significance of anti-C1q antibodies in cutaneous and systemic lupus erythematosus [PDF]

, 2012
Autoantibodies against C1q are strongly linked to immune-complex disorders like systemic lupus erythematosus (SLE). Although anti-C1q antibodies have received much interest in the recent years, their biological functions remain unclear.
Arafa, LF, Barakat, AF, El Gayyar, MA, Hegazy, A   +3 more
core   +1 more source

Emerging Topical and Systemic JAK Inhibitors in Dermatology [PDF]

, 2019
Accumulating data on cellular and molecular pathways help to develop novel therapeutic strategies in skin inflammation and autoimmunity. Examples are psoriasis and atopic dermatitis, two clinically and immunologically well-defined disorders.
Ghoreschi, Kamran, Meier, Katharina, Solimani, Farzan   +2 more
core   +1 more source

Clustering methods and Bayesian inference for the analysis of the evolution of immune disorders [PDF]

arXiv, 2020
Choosing appropriate hyperparameters for unsupervised clustering algorithms in an optimal way depending on the problem under study is a long standing challenge, which we tackle while adapting clustering algorithms for immune disorder diagnoses. We compare the potential ability of unsupervised clustering algorithms to detect disease flares and remission
arxiv  

Autoimmune diseases and their manifestations on oral cavity: diagnosis and clinical management [PDF]

, 2018
Oral signs are frequently the first manifestation of autoimmune diseases. For this reason, dentists play an important role in the detection of emerging autoimmune pathologies.
Bossù, Maurizio, Di Carlo, Gabriele, Giovarruscio, Francesca, Polimeni, Antonella, Saccucci, Matteo, Salucci, Alessandro   +5 more
core   +2 more sources

The contribution of extracellular RNA and its derived biomaterials in disease management

BMEMat, EarlyView.
The implications of exRNA's biological function and the structural uniqueness of RNA help establish a close connection between RNA, material, and modern medicine. Abstract The RNA found in the circular system is known as extracellular RNA (exRNA). This kind of RNA has been found to play a biological role similar to that of a messenger. They can be used
Yu Wei, Zhangyi Wang, Zixuan Qin, Qianqian Wan, Yutao Li, Franklin R. Tay, Chenyu Wang, Tong Zhang, Lina Niu   +8 more
wiley   +1 more source

Lupus mastitis and antiphospholipid syndrome treated with anticoagulation and immunosuppression: a case report

Journal of Medical Case Reports, 2023
Background Systemic lupus erythematosus is an autoimmune disease that can have cutaneous and systemic manifestations. Lupus panniculitis, also known as lupus mastitis, is a subset of chronic cutaneous lupus erythematosus that involves inflammation of the
Lauren J. He, Laarni C. Quimson, Oluwakemi Onajin, Kimberly C. Trotter   +3 more
doaj   +1 more source

Depressed serum IgM levels in SLE are restricted to defined subgroups [PDF]

, 2017
Natural IgM autoantibodies have been proposed to convey protection from autoimmune pathogenesis. Herein, we investigated the IgM responses in 396 systemic lupus erythematosus (SLE) patients, divided into subgroups based on distinct autoantibody profiles. Depressed IgM levels were more common in SLE than in matched population controls.
arxiv   +1 more source

GPA-Tree: Statistical Approach for Functional-Annotation-Tree-Guided Prioritization of GWAS Results [PDF]

arXiv, 2021
Motivation: In spite of great success of genome-wide association studies (GWAS), multiple challenges still remain. First, complex traits are often associated with many single nucleotide polymorphisms (SNPs), each with small or moderate effect sizes. Second, our understanding of the functional mechanisms through which genetic variants are associated ...
arxiv  

Cutaneous Force Feedback as a Sensory Subtraction Technique in Haptics [PDF]

D. Prattichizzo, C. Pacchierotti, G. Rosati. Cutaneous force feedback as a sensory subtraction technique in haptics. IEEE Transactions on Haptics, 5(4):289-300, 2012, 2011
A novel sensory substitution technique is presented. Kinesthetic and cutaneous force feedback are substituted by cutaneous feedback (CF) only, provided by two wearable devices able to apply forces to the index finger and the thumb, while holding a handle during a teleoperation task.
arxiv   +1 more source