Arthritis &Rheumatology, Volume 77, Issue 2, Page 212-225, February 2025.Objective Systemic inflammatory autoimmune diseases (SIADs) such as systemic lupus erythematosus (SLE), primary Sjögren disease (pSS), and idiopathic inflammatory myopathies (myositis) are complex conditions characterized by shared circulating autoantibodies and clinical manifestations, including skin rashes, among others.
Matteo Bianchi +109 more
wiley +1 more source
Integrated machine learning pipeline for aberrant biomarker enrichment (i-mAB): characterizing clusters of differentiation within a compendium of systemic lupus erythematosus patients [PDF]
arXiv, 2018 Clusters of differentiation (CD) are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies (mAB) afford rich trans-disease repositioning opportunities. Within a compendium of systemic lupus erythematous (SLE) patients, we applied the Integrated machine ...
arxiv
Barnes Hospital Bulletin [PDF]
, 1976 https://digitalcommons.wustl.edu/bjc_barnes_bulletin/1125/thumbnail ...
core +1 more source
How scientific literature has been evolving over the time? A novel statistical approach using tracking verbal-based methods [PDF]
JSM Proceedings (2014), Section on Statistical Learning and Data
Mining. Alexandria, VA. American Statistical Association. 1121-1131, 2016 This paper provides a global vision of the scientific publications related with the Systemic Lupus Erythematosus (SLE), taking as starting point abstracts of articles. Through the time, abstracts have been evolving towards higher complexity on used terminology, which makes necessary the use of sophisticated statistical methods and answering questions ...
arxiv
Classification on Large Networks: A Quantitative Bound via Motifs and Graphons [PDF]
arXiv, 2017 When each data point is a large graph, graph statistics such as densities of certain subgraphs (motifs) can be used as feature vectors for machine learning. While intuitive, motif counts are expensive to compute and difficult to work with theoretically. Via graphon theory, we give an explicit quantitative bound for the ability of motif homomorphisms to
arxiv
Population-based study of autoimmune conditions and the risk of specific lymphoid malignancies [PDF]
, 2009 Some autoimmune conditions are associated with increased risk of lymphoid malignancies, but information on specific malignancy subtypes is limited. From the U.S.
Anderson, Lesley +9 more
core +1 more source
Evidence for a Pathophysiological Role of Keratinocyte-Derived Type III Interferon (IFNλ) in Cutaneous Lupus Erythematosus [PDF]
, 2011 Type I IFNs (IFNα/β) have been shown to have a central role in the pathophysiology of lupus erythematosus (LE). The recently discovered type III IFNs (IFNλ1/IL29, IFNλ2/IL28a, IFNλ3/IL28b) share several functional similarities with type I IFNs ...
Bieber, Thomas +6 more
core +1 more source
Combined surgical techniques in the treatment of hypopigmented scars in discoid lupus erythematosus [PDF]
Surgical & Cosmetic DermatologyDiscoid lupus erythematosus (DLE) causes chronic lesions that can heal with dyschromic patches. We report a clinical case showing success in the treatment of achromic lesions using a combination of surgical techniques, including excision, punch grafting,
Rafael Rezende Rocha de Oliveira +4 more
doaj +1 more source
Visual Analytics of Group Differences in Tensor Fields: Application to Clinical DTI [PDF]
arXiv, 2017 We present a visual analytics system for exploring group differences in tensor fields with respect to all six degrees of freedom that are inherent in symmetric second-order tensors. Our framework closely integrates quantitative analysis, based on multivariate hypothesis testing and spatial cluster enhancement, with suitable visualization tools that ...
arxiv
Neonatal Lupus Erythematosus: New Serologic Findings [PDF]
, 1981 A child with neonatal lupus was evaluated and found to possess serum anti Ro(SSA) antibodies. The cutaneous lesions and anti Ro(SSA) antibodies disappeared during the next 5 mo.The infant's mother was asymptomatic but possessed anti Ro(SSA) and anti La ...
Hood, Antoinette F. +2 more
core +1 more source