Clinical, Cosmetic and Investigational DermatologyQing Zhu,1,2,* Yijia He,1,2,* Sijia Chen,1,2 Guoqiang Zhang1,2 1Department of Dermatology, The First Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Hebei Provincial Innovation Center of Dermatology and Medical ...
Zhu Q, He Y, Chen S, Zhang G
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Deep Reinforcement Learning for Personalized Diagnostic Decision Pathways Using Electronic Health Records: A Comparative Study on Anemia and Systemic Lupus Erythematosus [PDF]
arXivBackground: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from limitations as they are built to cover the majority of the population and fail at covering patients with uncommon ...
arxiv
Phenome-wide causal proteomics enhance systemic lupus erythematosus flare prediction: A study in Asian populations [PDF]
arXivObjective: Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by unpredictable flares. This study aimed to develop a novel proteomics-based risk prediction model specifically for Asian SLE populations to enhance personalized disease management and early intervention.
arxiv
A data-driven approach to discover and quantify systemic lupus erythematosus etiological heterogeneity from electronic health records [PDF]
arXivSystemic lupus erythematosus (SLE) is a complex heterogeneous disease with many manifestational facets. We propose a data-driven approach to discover probabilistic independent sources from multimodal imperfect EHR data. These sources represent exogenous variables in the data generation process causal graph that estimate latent root causes of the ...
arxiv
Solvated Membrane Nanodiscoids: A Probe For The Effects Of Gaussian Curvature [PDF]
arXiv, 2019 Several methods now exist to solvate lipid bilayer discoids at the scale of tens of nanometres. Due to their size, such nanodiscoids have a comparatively large boundary-to-area ratio, making them unusually well-suited to probing the effects of Gaussian curvature. Arguing that fluctuations in discoid size and shape are quenched on formation, we quantify
arxiv
Numerical solutions of a 2D fluid problem coupled to a nonlinear non-local reaction-advection-diffusion problem for cell crawling migration in a discoidal domain [PDF]
arXiv, 2018 In this work, we present a numerical scheme for the approximate solutions of a 2D crawling cell migration problem. The model, defined on a non-deformable discoidal domain, consists in a Darcy fluid problem coupled with a Poisson problem and a reaction-advection-diffusion problem.
arxiv
Indian Journal of Dermatology, 1997 Two cases with discoid lupus erythematosus (DLE) and lesions resembling erythema multiforme (EM), associated with depigmentation, are reported since DLE with EM and resultant depigmentation is rare.
Mittal R R, Garg Shivall
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Pellagroid discoid lupus erythematosus
Indian Journal of Medical Research, 2020 Anuja Yadav, Sarita Sanke
openaire +3 more sources
Lupus erythematosus comedonicus and vegetans: A challenging definition
JEADV Clinical PracticeA 39‐year‐old man presented with an acneiform facial eruption, bilateral vegetating erythematous plaques on the inguinal folds, focal palmoplantar keratoderma, keratotic violaceous plaques of the dorsum of both hands, and whitish striated lesions on the ...
Ana Sofia Pereira +3 more
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Effect Size-Driven Pathway Meta-Analysis for Gene Expression Data [PDF]
arXivThe proliferation of omics datasets in public repositories has created unprecedented opportunities for biomedical research but has also posed significant challenges for their integration, particularly due to missing genes and platform-specific discrepancies.
arxiv