Results 31 to 40 of about 132,280 (264)

Cognitive dysfunction improves in systemic lupus erythematosus: Results of a 10 years prospective study [PDF]

open access: yes, 2018
Objective Cognitive impairment (CI) has been described in 3–80% of Systemic lupus erythematosus (SLE) patients but only short-term studies evaluated its over-time changes, suggesting that CI is usually a stable finding. We aimed at evaluating the changes
Alessandri, Cristiano   +9 more
core   +12 more sources

Rapid efficacy of anifrolumab across multiple subtypes of recalcitrant cutaneous lupus erythematosus parallels changes in discrete subsets of blood transcriptomic and cellular biomarkers.

open access: yesBritish Journal of Dermatology, 2023
BACKGROUND Observations with rituximab suggest B-cell independent mechanisms of cutaneous lupus (CLE) in SLE, especially discoid. Type-I interferon receptor blockade with anifrolumab shows efficacy in SLE but efficacy on cutaneous disease of specific ...
L. Carter, Z. Wigston, P. Laws, E. Vital
semanticscholar   +1 more source

Ocular discoid lupus erythematosus: More than what meets the eye

open access: yesIndian Dermatology Online Journal, 2023
Lupus erythematosus is a spectrum that includes auto-immune disorders such as systemic lupus erythematosus (SLE), subacute cutaneous lupus erythematosus (SCLE), and chronic cutaneous lupus erythematosus (CCLE).
Sumiti Pareek   +3 more
doaj   +1 more source

Discoid lupus erythematosus in an infant

open access: yesDermatology Online Journal, 2005
Discoid lupus erythematosus (DLE) is rare in childhood. We report the case of a 15-month-old female infant who presented with erythematous telangectatic lesions and photosensitivity involving the sun-exposed areas. Histological examination confirmed the diagnosis of DLE.
T. Badri   +5 more
openaire   +4 more sources

Systemic lupus erythematosus with subacute cutaneous manifestation – acute on chronic.

open access: yesGalicia Clínica, 2018
Systemic Lupus Erythematosus (SLE) presents as a continuum, with some patients demonstrating only cutaneous manifestations, such as Chronic Cutaneous Lupus Erythematosus (CCLE) or other more severe organ manifestations as in SLE.
Juliana Lopes, Isabel Almeida
doaj   +1 more source

Nonisomorphic and nonisotopic multidermatomal discoid lupus erythematosus – A rare subtype of cutaneous lupus erythematosus

open access: yesIndian Dermatology Online Journal, 2020
Discoid lupus erythematosus (DLE) is the most common variant of chronic cutaneous lupus erythematosus. Several cases of Blaschko-linear lupus erythematosus, which is regarded as a distinct subtype of lupus erythematosus, have been reported across the ...
Sanjiv Choudhary   +3 more
doaj   +1 more source

Brief report: Responses to rituximab suggest B cell-independent inflammation in cutaneous systemic lupus erythematosus [PDF]

open access: yes, 2015
Objective The immunopathogenesis of systemic lupus erythematosus (SLE) is heterogeneous, and responses of skin to rituximab are variable. This study was undertaken to determine the phenotype of rituximab-responsive disease.
Berggren   +14 more
core   +1 more source

Generalized discoid lupus erythematosus

open access: yesDermatology Online Journal, 2009
A 79-year-old woman presented with a four-year history of generalized, erythematous, indurated plaques on the malar areas, back, and extremities. The lesions had been recalcitrant in the past to topical glucocorticoid therapy. A skin biopsy specimen was diagnostic of discoid lupus erythematosus (DLE). A minority of patients with DLE progress to develop
Farley-Loftus, Rachel   +6 more
openaire   +4 more sources

Creation and Validation of Classification Criteria for Discoid Lupus Erythematosus.

open access: yesJAMA dermatology, 2020
Importance Classification criteria are the standardized definitions that are used to enroll uniform cohorts for research studies. They emphasize high specificity and are distinct from diagnostic criteria. No universally recognized classification criteria
S. Elman   +12 more
semanticscholar   +1 more source

Effects of rituximab-based B-cell depletion therapy on skin manifestations of lupus erythematosus--report of 17 cases and review of the literature [PDF]

open access: yes, 2013
Cutaneous manifestations occur frequently in systemic lupus erythematosus (SLE) and are pathognomonic in subacute-cutaneous lupus erythematosus (SCLE) and chronic cutaneous lupus erythematosus (CCLE).
Hofmann, SC   +3 more
core   +1 more source

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