Results 141 to 150 of about 234,888 (250)

Thromboelastography Maximum Amplitude Is a Valuable Biomarker for Early Atherosclerosis in Rheumatoid Arthritis Patients: A Single‐Center Cross‐Sectional Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Hypercoagulability contributes to atherosclerosis (AS) progression in individuals suffering from rheumatoid arthritis (RA), and thromboelastography (TEG) is a valuable diagnostic tool. This hospital‐based cross‐sectional study assessed the clinical efficacy of TEG parameters in detecting hypercoagulability and subclinical AS by purposively ...
Qing‐Lin Zhang   +6 more
wiley   +1 more source

Deletion of NFIA Leads to Activation of S100A7 and Inflammatory Response‐Induced Apoptosis of Keratinocytes in Oral Lichen Planus Progression

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT S100 calcium‐binding protein A7 (S100A7) has been implicated in psoriasis and other inflammatory diseases. However, the function of S100A7 in oral lichen planus (OLP), a chronic inflammatory disease, remains unclear. OLP was induced in mice by transplanting human OLP lesions into the backs of thymus‐free mice, and an in vitro cell model was ...
Maimaiti Tudi   +3 more
wiley   +1 more source

Sciatic Nerve Stimulation Mitigates Depression‐Like Behaviors and Memory Deficits in Stressed Mice

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Stress causes depression and cognitive decline. With limitations in pharmacotherapy, sciatic nerve stimulation (SNS) offers a promising nondrug alternative. This study aimed to explore the therapeutic efficacy of SNS in mitigating stress‐induced depressive behaviors and memory deficits by focusing on astrocytic dysfunction and cellular ...
Chih‐Hao Tien   +10 more
wiley   +1 more source

Systemic Lupus Erythematosus [PDF]

open access: yesProceedings of the Royal Society of Medicine, 1971
openaire   +3 more sources

Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis

open access: yesMed Research, EarlyView.
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang   +7 more
wiley   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Upper extremity deep vein thrombosis associated with systemic lupus erythematosus and antiphospholipid syndrome

open access: yes
Journal of General and Family Medicine, EarlyView.
Masahiro Yabe   +6 more
wiley   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro   +5 more
wiley   +1 more source

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