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Nature Reviews Disease Primers, 2016
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Rare, inherited, single-gene complement deficiencies are strongly associated with SLE,
Arvind Kaul +2 more
exaly +11 more sources
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Rare, inherited, single-gene complement deficiencies are strongly associated with SLE,
Arvind Kaul +2 more
exaly +11 more sources
Systemic Lupus Erythematosus [PDF]
Journal of the American Academy of Nurse Practitioners, 1992 The reported change in the incidence of systemic lupus erythematosus (SLE) is mainly due to a greater awareness of the disease, and to the introduction of serological detection methods such as the LE cell assay and subsequently a variety of other antinuclear antibody assays.
Ruud J.T. Smeenk +2 more
openaire +5 more sources
Pediatric Clinics of North America, 2005
Systemic lupus erythematosus (SLE) in children and adolescents is a multisystem autoimmune disease with a great variability in disease presentation and course. The diagnosis of SLE is based on the clinical and laboratory features consistent with this illness in the absence of other autoimmune disease that could explain the findings.
Earl D. Silverman, Susanne M. Benseler
openaire +4 more sources
Systemic lupus erythematosus (SLE) in children and adolescents is a multisystem autoimmune disease with a great variability in disease presentation and course. The diagnosis of SLE is based on the clinical and laboratory features consistent with this illness in the absence of other autoimmune disease that could explain the findings.
Earl D. Silverman, Susanne M. Benseler
openaire +4 more sources
New England Journal of Medicine, 2008
In their review article, Rahman and Isenberg (Feb. 28 issue)1 emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.2 Interestingly, 36% of patients with type 1 autoimmune ...
Cynthia Aranow +2 more
openaire +4 more sources
In their review article, Rahman and Isenberg (Feb. 28 issue)1 emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.2 Interestingly, 36% of patients with type 1 autoimmune ...
Cynthia Aranow +2 more
openaire +4 more sources