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Systemic Lupus Erythematosus [PDF]

open access: yesNature Reviews Disease Primers, 2016
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect many organs, including the skin, joints, the central nervous system and the kidneys. Women of childbearing age and certain racial groups are typically predisposed to developing the condition. Rare, inherited, single-gene complement deficiencies are strongly associated with SLE,
Zahi Touma   +2 more
exaly   +12 more sources

Systemic Lupus Erythematosus

New England Journal of Medicine, 2008
In their review article, Rahman and Isenberg (Feb. 28 issue)1 emphasize the role of anti–double-stranded DNA antibodies in the pathogenesis of systemic lupus erythematosus. Such antibodies also occur, however, in 23 to 64% of patients with type 1 autoimmune hepatitis, depending on the assay used.2 Interestingly, 36% of patients with type 1 autoimmune ...
David A. Isenberg, Anisur Rahman
exaly   +5 more sources

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