Results 101 to 110 of about 1,279,892 (312)

A case of Lemierre syndrome combined with a suspected systemic lupus erythematosus flare

open access: yesSAGE Open Medical Case Reports, 2019
Lemierre syndrome develops in healthy young patients as a result of bacteremia after oral cavity infection. It causes thrombophlebitis in the internal jugular vein.
Teruhiro Fujii   +4 more
doaj   +1 more source

Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity [PDF]

open access: yes, 2005
When purified under rigorous conditions, some murine anti-double-stranded-DNA (anti-dsDNA) antibodies actually bind chromatin rather than dsDNA. This suggests that they may actually be antinucleosome antibodies that only appear to bind dsDNA when they ...
Lambrianides, A   +13 more
core   +1 more source

Omnidirectional Interaction Networks Modulating Phenotypic Plasticity in the Gut Microbiota Towards Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
This study employs a spouse‐pair cohort design and an idopNetwork model that integrates evolutionary game theory, predator‐prey dynamics, and developmental modularity theory to reconstruct maximally informative microbial interaction networks. This approach reveals how interspecies interactions drive the phenotypic plasticity of the gut microbiota in ...
Huizhen Li   +15 more
wiley   +1 more source

Systemic lupus erythematosus with subacute cutaneous manifestation – acute on chronic.

open access: yesGalicia Clínica, 2018
Systemic Lupus Erythematosus (SLE) presents as a continuum, with some patients demonstrating only cutaneous manifestations, such as Chronic Cutaneous Lupus Erythematosus (CCLE) or other more severe organ manifestations as in SLE.
Juliana Lopes, Isabel Almeida
doaj   +1 more source

Dysregulations in circulating sphingolipids associate with disease activity indices in female patients with systemic lupus erythematosus : a cross-sectional study

open access: yes, 2017
Objective The objective of this study was to investigate the association of clinical and renal disease activity with circulating sphingolipids in patients with systemic lupus erythematosus.
Jakobsson, P-J   +23 more
core   +1 more source

Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design

open access: yesAdvanced Science, EarlyView.
This review systematically elaborates on the mechanisms underlying physiological regulation and pathological dysregulation of biomolecular phase separation. It also summarizes advances in phase‑separation‑targeted therapeutic strategies and the design of functional biomaterials inspired by this process.
Jiawei Zhu   +5 more
wiley   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

open access: yesAdvanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu   +12 more
wiley   +1 more source

LP-199 Medications given to patients with incomplete systemic lupus erythematosus

open access: yesLupus Science and Medicine, 2023
Anastasiia Shumilova   +5 more
doaj   +1 more source

Fatal lupus flare presented as syndrome of inappropriate antidiuretic hormone secretion and hemorrhagic gastroenteritis: a case report

open access: yesDigital Diagnostics
Systemic lupus erythematosus is a multisystem autoimmune disease. The disease may have various manifestations and sometimes can be challenging to diagnose because of multiple clinical symptoms and their combinations. At the same time, early diagnosis may
Kira S. Dalgatova   +6 more
doaj   +1 more source

Erythematosus systemic lupus in Portugal: adherence and approach to medication therapy

open access: yes, 2016
Erythematosus Systemic Lupus is a chronic inflammatory disease that affects about half a million Europeans, more frequent in the southern countries and fertile women. The therapy adherence in this disease is not well known, particularly in Portugal.
Pinto, Isabel C.   +4 more
openaire   +1 more source

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