Results 111 to 120 of about 371,009 (363)

Comparison of Remission and Lupus Low Disease Activity State in Damage Prevention in a United States Systemic Lupus Erythematosus Cohort

Arthritis & Rheumatology, 2018
One objective in the treatment of systemic lupus erythematosus (SLE) disease activity is to reduce long‐term rates of organ damage. We undertook this study to analyze data from a large clinical SLE cohort to compare patients achieving different levels of
M. Petri, L. Magder
semanticscholar   +1 more source

Chilblain lupus erythematosus – a case report

Przegląd Dermatologiczny, 2015
Introduction . Chilblain lupus erythematosus is a chronic form of lupus erythematosus (LE) reported mostly in middle-aged female patients. Its characteristic manifestations are painful erythematous lesions on the acral parts of the body appearing after ...
Natalia Zając, Agnieszka Markiewicz, Katarzyna Chuchla-Szczupacka, Agnieszka Owczarczyk-Saczonek, Waldemar Placek   +4 more
doaj   +1 more source

Endogenous Retroelement Activation is Implicated in Interferon‐α Production and Anti–Cyclic Citrullinated Peptide Autoantibody Generation in Early Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Endogenous retroelements (EREs) stimulate type 1 interferon (IFN‐I) production but have not been explored as potential interferonogenic triggers in rheumatoid arthritis (RA). We investigated ERE expression in early RA (eRA), a period in which IFN‐I levels are increased.
Faye A. H. Cooles, Gemma Vidal Pedrola, Najib Naamane, Arthur G. Pratt, Ben Barron‐Millar, Amy E. Anderson, Catharien M. U. Hilkens, John Casement, Vincent Bondet, Darragh Duffy, Fan Zhang, Ruchi Shukla, John D. Isaacs   +12 more
wiley   +1 more source

Integrated machine learning pipeline for aberrant biomarker enrichment (i-mAB): characterizing clusters of differentiation within a compendium of systemic lupus erythematosus patients [PDF]

arXiv, 2018
Clusters of differentiation (CD) are cell surface biomarkers that denote key biological differences between cell types and disease state. CD-targeting therapeutic monoclonal antibodies (mAB) afford rich trans-disease repositioning opportunities. Within a compendium of systemic lupus erythematous (SLE) patients, we applied the Integrated machine ...
arxiv  

The Spitzer Survey of Interstellar Clouds in the Gould Belt. IV. Lupus V and VI Observed with IRAC and MIPS [PDF]

, 2011
We present Gould's Belt (GB) Spitzer IRAC and MIPS observations of the Lupus V and VI clouds and discuss them in combination with near-infrared (2MASS) data. Our observations complement those obtained for other Lupus clouds within the frame of the Spitzer "Core to Disk" (c2d) Legacy Survey.
arxiv   +1 more source

Neuropsychiatric Lupus Erythematosus

Reumatismo, 2011
Neuropsychiatric involvement in patients with Systemic Lupus Erythematosus (SLE), first mentioned by Kaposi more than 100 years ago, still remains one of the main challenge facing rheumatologist and other physicians. The diagnosis of neuropsychiatric SLE (NPSLE) is complex not only because of the considerable prevalence variation (14-80%) but also ...
Vadacca M, Buzzulini F, Rigon A, Coppolino G, Palma Modoni A, Massa R, Antonella Maria Vittoria Afeltra   +6 more
openaire   +5 more sources

Drug-induced lupus erythematosus: an update on drugs and mechanisms

Current Opinion in Rheumatology, 2018
Purpose of review Rapid introduction of newly developed drugs in the absence of clear understanding of the pathophysiologic mechanisms behind drug-induced lupus erythematosus (DILE) can sometimes make DILE difficult to recognize in clinical practice. The
Ye He, A. Sawalha
semanticscholar   +1 more source

Atherosclerotic Plaque Progression and Incident Cardiovascular Events in a 10‐Year Prospective Study of Patients With Systemic Lupus Erythematosus: The Impact of Persistent Cardiovascular Risk Factor Target Attainment and Sustained DORIS Remission

Arthritis &Rheumatology, EarlyView.
Objective Cardiovascular disease (CVD) is a leading cause of death in individuals with systemic lupus erythematosus (SLE). We assessed atherosclerotic plaque progression and incident cardiovascular events in patients with SLE over a 10‐year follow‐up.
Nikolaos Papazoglou, Petros P. Sfikakis, Maria G. Tektonidou   +2 more
wiley   +1 more source

How scientific literature has been evolving over the time? A novel statistical approach using tracking verbal-based methods [PDF]

JSM Proceedings (2014), Section on Statistical Learning and Data Mining. Alexandria, VA. American Statistical Association. 1121-1131, 2016
This paper provides a global vision of the scientific publications related with the Systemic Lupus Erythematosus (SLE), taking as starting point abstracts of articles. Through the time, abstracts have been evolving towards higher complexity on used terminology, which makes necessary the use of sophisticated statistical methods and answering questions ...
arxiv  

How Do Patients With Newly Diagnosed Systemic Lupus Erythematosus Present? A Multicenter Cohort of Early Systemic Lupus Erythematosus to Inform the Development of New Classification Criteria

Arthritis & Rheumatology, 2018
Systemic lupus erythematosus (SLE) presents with nonspecific signs and symptoms that are also found in other conditions. This study aimed to evaluate manifestations at disease onset and to compare early SLE manifestations to those of diseases mimicking ...
M. Mosca, K. Costenbader, S. Johnson, V. Lorenzoni, G. Sebastiani, B. Hoyer, S. Navarra, E. Bonfá, R. Ramsey‐Goldman, J. Medina-Rosas, M. Piga, C. Tani, S. Tedeschi, T. Dörner, M. Aringer, Z. Touma   +15 more
semanticscholar   +1 more source