Results 121 to 130 of about 371,513 (350)

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

LP-126 The infectious complication in multitarget therapy of class V lupus nephritis: a case report

Lupus Science and Medicine, 2023
Anastasiia Shumilova, Tatiana Popkova, Tatiana Panafidina, Aleksandr Lila   +3 more
doaj   +1 more source

For the eye altering, alters the all [PDF]

, 2015
C
Boey, Olivier, Bogaert, Anne-Marie, De Scheerder, Marie-Angélique, Mahieu, Elien, Vanuytsel, Johan   +4 more
core   +1 more source

Pulmonary arterial hypertension in systemic lupus erythematosus may benefit by addition of immunosuppression to vasodilator therapy: an observational study [PDF]

, 2015
Sirisha Kommireddy, Srinivas Bhyravavajhala, Kishorebabu Kurimeti, Srinivasa Chennareddy, S Kanchinadham, Irlapati Rajendra Vara Prasad, Liza Rajasekhar   +6 more
openalex   +1 more source

44 Pediatric onset systemic lupus erythematosus (p-SLE) [PDF]

, 2022
Sheren Esam Maher
openalex   +1 more source

Cleavage‐Resistant CYLD Protects Against Autoimmune Hepatitis

Advanced Science, EarlyView.
Proteolytic cleavage of the deubiquitinase CYLD emerges as a critical driver of autoimmune hepatitis. TNFα‐induced CYLD loss in macrophages amplifies S100A9‐triggered MAPK activation, leading to excessive chemokine production and hepatic inflammation. Pharmacological inhibition of MEK signaling effectively attenuates experimental disease, highlighting ...
Han Liu, Chen Su, Jianling Liu, Mingyan Xing, Xiaoxia Wu, Lingxia Wang, Xiaoming Zhao, Hanwen Zhang, YangYang Xie, YangYang Wang, Hong Li, Yu Li, Ming Li, Haibing Zhang   +13 more
wiley   +1 more source

LP-113 Systemic lupus erythematosus induced by experimental therapy with a combination of monoclonal antibodies against the sars-cov2 surface s-protein

Lupus Science and Medicine, 2023
Mariia Aristova, Tatiana Popkova, Tatiana Panafidina, Anna Misiyuk, Magomed Kurbanmagomedov   +4 more
doaj   +1 more source

Scleroderma-Like Lupus Panniculitis: A Case Report and Literature Review

Clinical, Cosmetic and Investigational Dermatology, 2023
Prinpat Pinyowiwat, Suthinee Rutnin, Kumutnart Chanprapaph Division of Dermatology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, ThailandCorrespondence: Kumutnart Chanprapaph, Division of Dermatology ...
Pinyowiwat P, Rutnin S, Chanprapaph K
doaj  

Precision Medicine in Systemic Lupus Erythematosus [PDF]

, 2023
Evan Kimber
openalex   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

Advanced Science, EarlyView.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei, Huiyan Ji, Jing Guo, Mengdi Liu, Danhua Su, Yiran Zheng, Lin Xu, Qinghua Cao, Tao Ren, Jun Gui, Zhenke Wen   +10 more
wiley   +1 more source