Results 61 to 70 of about 411,697 (349)

Determinant Factors of Morbidity in Patients with Systemic Lupus Erythematosus

open access: yesActa Médica Portuguesa, 2017
Introduction: Severity in systemic lupus erythematosus may vary from mild to even fatal consequences. There are no biomarkers to predict the disease’s prognosis.
Margarida Jacinto   +3 more
doaj   +1 more source

Neonatal Lupus Erythematosus

open access: yesJournal of Investigative Dermatology, 1993
Neonatal lupus erythematosus (NLE) is an autoimmune disease whose major findings are subacute cutaneous lupus erythematosus (SCLE) skin lesions and congenital heart block. Babies have maternal anti-Ro/SSA, anti-La/SSB, or anti-U1RNP autoantibodies. Anti-Ro/SSA are the predominant autoantibodies, having been found in about 95% of cases.
openaire   +3 more sources

LUPUS ERYTHEMATOSUS [PDF]

open access: yesBritish Journal of Dermatology, 1901
n ...
openaire   +1 more source

Identifying High‐Impact Solutions to Address Racial and Ethnic Health Disparities in Lupus: A Consensus‐Based Approach

open access: yesArthritis Care &Research, Accepted Article.
Objective We conducted formative research aimed at identifying solutions that address inequitable health outcomes in lupus due to adverse social determinants of health. Methods We conducted a search for keywords which provided insights into potential solutions and initiatives underway. An advisory panel of lupus experts iteratively reviewed the list of
Joy Buie   +11 more
wiley   +1 more source

Serum interleukin-17 levels are associated with nephritis in childhood-onset systemic lupus erythematosus

open access: yesClinics, 2015
OBJECTIVES: To determine the serum interleukin-17 (IL-17) levels in childhood-onset systemic lupus erythematosus patients and to evaluate the association between IL-17 and clinical manifestations, disease activity, laboratory findings and treatment ...
Karina de Oliveira Peliçari   +7 more
doaj   +1 more source

Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2019
Significance The field of neutrophil biology has lagged behind in terms of the understanding of heterogeneity and versatility of cellular functions, limiting the development of therapeutic approaches that target aberrant neutrophil phenotypes. Using bulk
Pragnesh Mistry   +18 more
semanticscholar   +1 more source

Prevalence, determinants and outcomes of low disease activity and remission attainment in SLE patients with clinically active disease

open access: yesArthritis Care &Research, Accepted Article.
Objectives This study aimed to identify the frequency and determinants of Lupus Low Disease Activity State (LLDAS) and Definition of Remission in SLE (DORIS‐remission) attainment in systemic lupus erythematosus (SLE) patients with clinically active disease, and the frequency and determinants of flare and damage accrual after target attainment.
Yanjie Hao   +39 more
wiley   +1 more source

Age-related changes in Serum Growth Hormone, Insulin-like Growth Factor-1 and Somatostatin in System Lupus Erythematosus

open access: yesBMC Musculoskeletal Disorders, 2004
Background Systemic lupus erythematosus is an age- and gender-associated autoimmune disorder. Previous studies suggested that defects in the hypothalamic/pituitary axis contributed to systemic lupus erythematosus disease progression which could also ...
Malemud Charles J, Denko Charles W
doaj   +1 more source

Serum soluble mediator signatures of lupus nephritis: histological features and response to treatment

open access: yesArthritis Care &Research, Accepted Article.
Objective Lupus nephritis (LN) management remains challenging, and novel noninvasive biomarkers are needed. This study quantified serum soluble mediators in the Accelerating Medicines Partnership (AMP) LN cohort to identify biomarkers of histological features and treatment response.
Andrea Fava   +26 more
wiley   +1 more source

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