Results 91 to 100 of about 109,330 (215)

New Insights on Childhood Lupus Nephritis [PDF]

Rodrigo Marchi-Silva,1,2 Bruna Martins De Aquino,1,2 Ana Carolina Londe,1,2 Ta&iacgr;s Nitsch Mazzola,3 Paulo Rogério Julio,4 Theresa Wampler Muskardin,5,6 Simone Appenzeller2,7 1Medical Pathophysiology Graduate Program, School of Medical Science ...
Marchi-Silva R, De Aquino BM, Wampler Muskardin T, Londe AC, Appenzeller S, Julio PR, Mazzola TN   +6 more
core  

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

Current status of research on the pathophysiological mechanisms and urinary biomarkers of lupus nephritis

Linchuang shenzangbing zazhi
Lupus nephritis is an immune complex （IC）-mediated nephritis caused by renal involvement in systemic lupus erythematosus， and it is one of the major causes of death and progression to end-stage renal disease in patients with systemic lupus erythematosus.
Wang Jing-ying, Lu Yan
doaj  

The Dual Role of Microbiota as a Therapeutic Target in Lupus Nephritis

Turkish Journal of Nephrology
Lupus nephritis, a severe manifestation of systemic lupus erythematosus (SLE), involves kidney inflammation driven by immune dysregulation. Emerging evidence highlights gut microbiota as a key factor in lupus nephritis pathogenesis, with dysbiosis ...
Ramesa Shafi Bhat
doaj   +1 more source

Correlation of Random Urine Protein Creatinine (P-C) Ratio with 24-Hour Protein Urine in Lupus Nephritis Patients

Indonesian Journal of Rheumatology, 2018
Background : Systemic lupus erythematosus (SLE) is a systemic autoimmune disease involving multiple organs including kidney and known as lupus nephritis (LN). Lupus nephritis has a poor prognosis after a 10-years onset, more than 25% will be ended by end
Y H Aini, A Tjandrawati, N Suraya, Laniyati Hamijoyo   +3 more
doaj   +1 more source

Lupus nephritis: Induction therapy

, 2005
Effective induction therapy is of pivotal importance in minimizing renal parenchymal damage by the active immune-mediated inflammatory processes in severe proliferative lupus nephritis.
Chan, TM
core   +1 more source

Extended routine lymphocyte immunophenotyping refines individual immune organization across a heterogeneous patient cohort

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Routine TBNK immunophenotyping detects the major lymphocyte compartments but may underestimate the biologically relevant variation contributed by less frequent but well‐defined minor lymphocyte subsets. This study evaluated whether extending routine TBNK immunophenotyping with minor lymphocyte subsets provides complementary, analytically ...
Carlos Agustin Villegas Valverde, Yendry Ventura Carmenate, Vianed Marsan Suarez, Yandy Marx Castillo Aleman, Imilla Casado Hernandez, Rachely Hernandez Corrales   +5 more
wiley   +1 more source

Reassessing the role of antiphospholipid antibodies in placental‐mediated adverse pregnancy outcomes in systemic lupus erythematosus: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To examine how different antiphospholipid antibody (aPL) profiles influence placental‐mediated adverse pregnancy outcomes (APOs) in women with systemic lupus erythematosus (SLE). Methods This retrospective cohort study included 245 pregnant women with SLE and 490 controls from a single center.
Meng Jiang, Yanling Chang, Ning Zhang, Wen Di, Jiayue Wu   +4 more
wiley   +1 more source

The Clinicopathological Study of Lupus Nephritis

Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2014
Purpose: Lupus nephritis is one of the most serious manifestations of Systemic lupus erythematosis and it is a major cause of morbidity and mortality. The aim of this study is to compare males and females in lupus nephritis presentations.
Raouf Rahim Merza, Ayar Omer Ali, Hawar Ali Ehsan Kaka Khan   +2 more
doaj  

Successful Management Strategies for Lupus Nephritis in the Intensive Care Unit: A Case Series

Archives of Anesthesia and Critical Care
Lupus nephritis, a severe complication of systemic lupus erythematosus (SLE), often leads to significant renal impairment requiring intensive care. The management of lupus nephritis in the intensive care unit of Dr.
Achmad Marwan, Bambang Pujo Semedi, Maulydia Maulydia   +2 more
doaj   +1 more source