Results 71 to 80 of about 37,260 (216)
Clinical Pharmacology &Therapeutics, EarlyView.Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor +12 more
wiley +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Routine TBNK immunophenotyping detects the major lymphocyte compartments but may underestimate the biologically relevant variation contributed by less frequent but well‐defined minor lymphocyte subsets. This study evaluated whether extending routine TBNK immunophenotyping with minor lymphocyte subsets provides complementary, analytically ...
Carlos Agustin Villegas Valverde +5 more
wiley +1 more source
Anti phospholipid Syndrome Nephropathy in Patients with Lupus Nephritis
مجله دانشکده پزشکی اصفهان, 2008 Increasing the Antiphospholipid-nephropathy (APS-N) alterations on lupus renal lesions cause renal disease progression and detoriation of prognosis. The aim of this study was to find some indicators in lupus patients that can predict the occurring ...
Ali Sadoogh Abbasian +2 more
doaj
An Unusual Initial Presentation of Lupus Nephritis as a Renal Mass
Case Reports in Nephrology, 2015 Lupus nephritis is a frequent manifestation of systemic lupus erythematous. Lupus nephritis usually presents with abnormal urinalysis, proteinuria, and/or renal insufficiency.
Remi Goupil +4 more
doaj +1 more source
International Journal of Gynecology &Obstetrics, EarlyView.Abstract Objective To examine how different antiphospholipid antibody (aPL) profiles influence placental‐mediated adverse pregnancy outcomes (APOs) in women with systemic lupus erythematosus (SLE). Methods This retrospective cohort study included 245 pregnant women with SLE and 490 controls from a single center.
Meng Jiang +4 more
wiley +1 more source
Belitung Nursing JournalBackground: Patients with lupus nephritis experience disease symptoms and side effects from treatment. Although self-management behaviors are important in patients with this disease, there is limited research on the factors influencing these behaviors ...
Sirikarn Hanrop +4 more
doaj +1 more source
The Turkish Journal of Gastroenterology, 2022 Objectives: This study aims to investigate the prevalence of low-density lipoprotein receptor (LDL-R) rs5925 genetic variants and to evaluate their relationship with plasma lipid and kidney functions in lupus nephritis patients. Patients and methods:
Yumn A. Alsabbagh +4 more
doaj
Epigenetic Regulation in the Pathogenesis of Renal Inflammation: Insights and Therapeutic Potentials
iNew Medicine, EarlyView.ABSTRACT Renal inflammation is a common pathological process in various kidney diseases, often initiated by factors such as toxins, ischemia, or autoimmune reactions. This inflammatory response can result in structural damage and a rapid decline in renal function.
Yu‐Hang Dong +5 more
wiley +1 more source
TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu +8 more
wiley +1 more source
Impact of lupus nephritis on foeto-maternal outcomes: a retrospective case-control study
Journal of the Pakistan Medical AssociationObjective: To evaluate the impact of lupus nephritis on foeto-maternal outcomes in patients with systemic lupus erythematosus, and to compare it with those without lupus nephritis.
dur-e- shahwar +3 more
doaj +1 more source