Results 211 to 220 of about 65,459 (255)
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Journal of the American Society of Nephrology, 1999
Effective treatment of lupus nephritis requires an understanding of disease pathogenesis, risk stratification by World Health Organization (WHO) classification and therapeutic options. Mesangial lupus nephropathy is generally associated with an excellent prognosis, whereas proliferative lupus nephropathy, especially the diffuse variant, is often ...
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Effective treatment of lupus nephritis requires an understanding of disease pathogenesis, risk stratification by World Health Organization (WHO) classification and therapeutic options. Mesangial lupus nephropathy is generally associated with an excellent prognosis, whereas proliferative lupus nephropathy, especially the diffuse variant, is often ...
+6 more sources
Therapeutische Umschau, 2005
Die Lupus Nephritis ist eine schwere Erkrankung und ein wichtiger Organbefall beim Vorliegen eines Systemischen Lupus Erythematodes (SLE). Eine rasche Diagnose mit anschließender Behandlung ist entscheidend, um eine relevante Organschädigung mit erhöhter Morbidität und Mortalität nach Möglichkeit zu verhindern.
J, Steiger, D, Garzoni, M, Mayr
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Die Lupus Nephritis ist eine schwere Erkrankung und ein wichtiger Organbefall beim Vorliegen eines Systemischen Lupus Erythematodes (SLE). Eine rasche Diagnose mit anschließender Behandlung ist entscheidend, um eine relevante Organschädigung mit erhöhter Morbidität und Mortalität nach Möglichkeit zu verhindern.
J, Steiger, D, Garzoni, M, Mayr
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Current Opinion in Rheumatology, 1996
Both immune and nonimmune mechanisms are operant in lupus nephritis. Recent findings have begun to elucidate fundamental questions in the pathogenesis of the disease. Genetic linkage studies have identified susceptibility loci contributing to nephritis in lupus-prone mice.
J C, Davis, I O, Tassiulas, D T, Boumpas
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Both immune and nonimmune mechanisms are operant in lupus nephritis. Recent findings have begun to elucidate fundamental questions in the pathogenesis of the disease. Genetic linkage studies have identified susceptibility loci contributing to nephritis in lupus-prone mice.
J C, Davis, I O, Tassiulas, D T, Boumpas
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Clinical Immunology, 2017
Lupus nephritis (LN), a potentially destructive outcome of SLE, is a real challenge in the management of SLE because of the difficulty in diagnosing its subclinical onset and identifying relapses before serious complications set in. Conventional clinical parameters such as proteinuria, GFR, urine sediments, anti-dsDNA and complement levels are not ...
Samar, Soliman, Chandra, Mohan
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Lupus nephritis (LN), a potentially destructive outcome of SLE, is a real challenge in the management of SLE because of the difficulty in diagnosing its subclinical onset and identifying relapses before serious complications set in. Conventional clinical parameters such as proteinuria, GFR, urine sediments, anti-dsDNA and complement levels are not ...
Samar, Soliman, Chandra, Mohan
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Current Opinion in Nephrology and Hypertension, 1995
Lupus nephritis is a major cause of morbidity and mortality arising from systemic lupus erythematosus. The pathology seen on renal biopsy and clinical features of renal involvement remain major prognostic factors and therapeutic guides. Serologic markers also correlate with disease activity, but more significantly, the identification of cationic and ...
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Lupus nephritis is a major cause of morbidity and mortality arising from systemic lupus erythematosus. The pathology seen on renal biopsy and clinical features of renal involvement remain major prognostic factors and therapeutic guides. Serologic markers also correlate with disease activity, but more significantly, the identification of cationic and ...
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Lupus, 2005
Membranous lupus nephritis (MLN) represents about 20% of clinically significant renal disease in lupus. Few studies have addressed directly the pathogenesis of MLN. Our assumptions about the underlying mechanisms are based on the combination of extrapolations from idiopathic membranous nephritis (mainly from animal models) and proliferative lupus ...
H A, Austin, G G, Illei
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Membranous lupus nephritis (MLN) represents about 20% of clinically significant renal disease in lupus. Few studies have addressed directly the pathogenesis of MLN. Our assumptions about the underlying mechanisms are based on the combination of extrapolations from idiopathic membranous nephritis (mainly from animal models) and proliferative lupus ...
H A, Austin, G G, Illei
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Lupus, 2005
The clinical course of lupus nephritis varies remarkably among SLE patients, even between those with the same histological type. Current immunosuppressive agents induce remission in the majority of the patients with proliferative lupus nephritis, but a substantial proportion of them - ranging in different studies from 27% to 66% - will flare.
P I, Sidiropoulos +2 more
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The clinical course of lupus nephritis varies remarkably among SLE patients, even between those with the same histological type. Current immunosuppressive agents induce remission in the majority of the patients with proliferative lupus nephritis, but a substantial proportion of them - ranging in different studies from 27% to 66% - will flare.
P I, Sidiropoulos +2 more
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Lupus Nephritis: Induction Therapy
Lupus, 2005Effective induction therapy is of pivotal importance in minimizing renal parenchymal damage by the active immune-mediated inflammatory processes in severe proliferative lupus nephritis. Preservation of nephron mass is prerequisite to long-term renal survival.
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Lupus nephritis (LN) or renal involvement of systemic lupus erythematosus (SLE), is a common manifestation occurring in at least 50 % of SLE patients. LN remains a significant source of morbidity, often leading to progressive renal dysfunction and is a major cause of death in SLE.
Chrisanna, Dobrowolski +8 more
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Chrisanna, Dobrowolski +8 more
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