Results 131 to 140 of about 14,841 (289)

NSUN2‐Mediated m5C Modification of TGFB1 in Trophoblasts Remodels Macrophage Function to Prevent URSA

open access: yesAdvanced Science, EarlyView.
NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu   +10 more
wiley   +1 more source

Luster

open access: yes, 2012
Luster is a novel that explores how the life trajectories of several characters are entangled and disrupted by a single tragic event. Aaron and his girlfriend Nev discover the body of Susan Hayward in the shoals of a Western Pennsylvanian creek. Although
Ringle, Evan Lawrence
core  

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

open access: yesAdvanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu   +14 more
wiley   +1 more source

Influence of Ru Content on Defect Formation and Electrocatalytic Activity of Au‐Pd‐Pt‐Ru Compositionally Complex Solid Solution Thin Films for the Hydrogen Evolution Reaction

open access: yesAdvanced Science, EarlyView.
Transmission electron microscopy reveals that the formation of planar defects in Au–Pd–Pt–Ru CCSS thin films depends on Ru content, which in turn influences hydrogen evolution reaction electrocatalytic activity. As the Ru content increases, the density of nanotwins initially rises; with further Ru addition, stacking faults form.
Miran Joo   +10 more
wiley   +1 more source

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

open access: yesAdvanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li   +13 more
wiley   +1 more source

Inheritance of Seed Color, Size and Luster in Mungbean (Vigna radiata (L.) Wilzeck)

open access: yes, 1972
Eight cross combinations from four mungbean accessions were studied up to the F2 to determine the mode of inheritance of need color, size and luster. Sees color was found monogenically inherited with green dominant to yellow.
Manguiat, Proceso H
core  

Distinct Cleavage Trajectories Mediated by DNA and RNA Substrate in Argonaute From Methanocaldococcus Fervens

open access: yesAdvanced Science, EarlyView.
This study characterizes MfAgo, an enzyme exhibiting highly efficient DNA‐guided DNA and RNA cleavage capability. Precise RNA cleavage strictly requires dimerization to stabilize the PIWI‐loop region, while its robust DNA cleavage functions in a dimerization‐independent manner.
Fuyong Huang   +9 more
wiley   +1 more source

Substance use involvement moderates the effect of cortisol response on white-matter microstructure longitudinally. [PDF]

open access: yesDialogues Clin Neurosci
Smith CE   +5 more
europepmc   +1 more source

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