Results 141 to 150 of about 14,841 (289)
Self‐Assembling Peptide‐Adjuvant Conjugate (SaPAC) Platform for Precision Cancer Immunotherapy
Advanced Science, EarlyView.A self‐assembling peptide–adjuvant conjugate links neoantigens to TLR7 agonism, forming cationic nanoparticles that enhance lymph‐node retention, dendritic‐cell activation, and antitumor T‐cell immunity. This chemically defined platform shows how synchronized antigen and innate stimulation can be adapted across melanoma, bladder cancer, and triple ...
Yang‐Fan Wu +15 more
wiley +1 more source
Advanced Science, EarlyView.A novel geometry‐resolved membrane platform provides a seamlessly integrated pipeline for studying curvature‐sensing proteins. By linking shotgun proteomics with quantitative imaging, this approach enables both the unbiased discovery and rigorous validation of novel sensors across the entire curvature range—positive, negative, and zero.
Takumi Komikawa +6 more
wiley +1 more source
Taxonomic notes on the Chinese species of the genus <i>Broscosoma</i> Rosenhauer, 1846 (Coleoptera, Carabidae, Broscinae), with description of seven new species. [PDF]
ZookeysJiang RX, Chen JH, Li ZZ, Chen XS.
europepmc +1 more source
Judge Luster Cook being sworn into office by Dist.
Judge Luster Cook being sworn into office by Dist.
core
Vitamin D in asthma: Is the golden bullet losing its luster?
, 2016 Vitamin D in asthma: Is the golden bullet losing its ...
JW Upham (14458044), PD Sly (14453628)
core
Advanced Science, EarlyView.Biomineralization underpins skeletal development, yet its molecular control remains incompletely understood. Using a novel murine knockout model, this study reveals the essential and complementary roles of PHOSPHO1 and TNAP in postnatal skeletal development.
Lucie E. Bourne +15 more
wiley +1 more source
Regulatory T-cell-biased IL-2 mutein inhibits development of allergen-specific T<sub>H</sub>2 cells and allergic asthma. [PDF]
J Allergy Clin ImmunolSelle A +4 more
europepmc +1 more source
Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer
Advanced Science, EarlyView.Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang +17 more
wiley +1 more source
Advanced Science, EarlyView.A high‐throughput screening platform was established by integrating an in vivo cadaverine biosensor with a fluorescence‐activated cell sorting (FACS) system. Biosensor‐driven specific exporter tuning, pathway optimization and genome‐wide target mining were conducted to maximize cadaverine production in Escherichia coli.
Jia Feng +13 more
wiley +1 more source
Long-Term Clinical Performance of Posterior Composite Restorations After Nearly Three Decades: A Clinical Follow-Up Study. [PDF]
Dent J (Basel)Singh K +5 more
europepmc +1 more source