Results 161 to 170 of about 14,841 (289)

High‐Density Type I Collagen Promotes IFN‐γ+ CD8+ T Cell Exhaustion via SAT1‐ASS1‐Mediated Glutamine Accumulation and Ferroptosis in Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
High‐density type I collagen promotes glutamine (Gln) accumulation–related ferroptosis of TNBC cells via the spermidine/spermine N1‐acetyltransferase 1 (SAT1)‐ argininosuccinate synthase (ASS1) signaling pathway, thus depriving immune cells of Gln supply and inducing IFN‐γ+ CD8+ T cell exhaustion in the TME.
Jinyan Wang   +11 more
wiley   +1 more source

Neurodegenerative mortality among National Football League Players. [PDF]

open access: yesEClinicalMedicine
Luster CB   +13 more
europepmc   +1 more source

Platycodon grandiflorus–Derived Nanovesicles Sensitize Gastric Cancer to T Cell Killing via Ferroptosis‐Driven Membrane Mechanical Remodeling

open access: yesAdvanced Science, EarlyView.
Plant‐derived nanovesicles from Platycodon grandiflorus act as bioactive lipid delivery platforms that transport γ‐linolenic acid into gastric cancer cells. This lipid cargo promotes ferroptotic lipid peroxidation, remodels membrane mechanics, and increases tumor‐cell susceptibility to cytotoxic T‐cell attack.
Jian Wu   +9 more
wiley   +1 more source

Enhancing Quasi‐Two‐Dimensional Electronic Structure in Bi2O2Se via Chlorine Substitution

open access: yesAdvanced Science, EarlyView.
We demonstrate chlorine substitution as an effective strategy to transform Bi2O2Se into an exfoliatable van der Waals superlattice. Key electronic band feature, including indirect bandgap, effective mass is well preserved, while the 2D character of the system is sufficiently enhanced.
Yong‐Zhen Jiang   +19 more
wiley   +1 more source

Neurodegenerative Disease Death Certification Among National Football League Players With Dementia.

open access: yesJAMA Netw Open
Luster CB   +15 more
europepmc   +1 more source

Engineered Allosteric Biosensor for In Situ DNA Glycosylase Detection in Neuroblastoma Risk Stratification and Drug Resistance Monitoring

open access: yesAdvanced Science, EarlyView.
An engineered allosteric biosensor (UUU‐DZ‐tFNA) was developed, in which UDG specifically recognizes and activates a DNAzyme to achieve signal cycle amplification in a sequentially activatable mode. UUU‐DZ‐tFNA achieves in situ UDG detection across multiple biological levels and facilitates risk stratification and drug resistance monitoring of NB ...
Yaqing Lu   +10 more
wiley   +1 more source

IL-2 mutein promotes antigen-specific transplant acceptance in mice through expansion of ST2<sup>+</sup> regulatory T cells. [PDF]

open access: yesNat Commun
Ganchiku Y   +13 more
europepmc   +1 more source

Sodiophilic Na3Sb Framework‐Regulated Sodium Deposition and Interphase Evolution for Dendrite‐Free and Long‐Life Sodium Metal Batteries

open access: yesAdvanced Science, EarlyView.
An interconnected sodiophilic Na3Sb framework embedded within a metallic Na matrix enables uniform Na deposition by homogenizing Na+ flux and providing abundant nucleation sites. Simultaneously, the regulated interface promotes the formation of a stable, NaF‐rich inorganic interphase, collectively suppressing dendrite growth and enabling highly ...
So Hyun Lee   +7 more
wiley   +1 more source

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